• Feedback
  • RIVM

Webbased Archive of RIVM Publications

Collection All
Listed communities

Webbased Archive of RIVM Publications > Articles and other publications by RIVM employees > Miscellaneous > Evaluation of a procedure to assess the adverse effects of illicit drugs.

Please use this identifier to cite or link to this item: http://hdl.handle.net/10029/12622
    Del.icio.us     LinkedIn     Citeulike     Connotea     Facebook     Stumble it!

Title: Evaluation of a procedure to assess the adverse effects of illicit drugs.
Authors: Amsterdam, J G C van
Best, W
Opperhuizen, A
Wolff, F A de
Citation: Regul. Toxicol. Pharmacol. 2004, 39(1):1-4
Issue Date: 1-Feb-2004
URI: http://hdl.handle.net/10029/12622
PubMed ID: 14746774
Abstract: The assessment procedure of new synthetic illicit drugs that are not documented in the UN treaty on psychotropic drugs was evaluated using a modified Electre model. Drugs were evaluated by an expert panel via the open Delphi approach, where the written score was discussed on 16 items, covering medical, health, legal, and criminalistic issues of the drugs. After this face-to-face discussion the drugs were scored again. Taking the assessment of ketamine as an example, it appeared that each expert used its own scale to score, and that policymakers do not score deviant from experts trained in the medical-biological field. Of the five drugs evaluated by the panel, p-methoxy-metamphetamine (PMMA), gamma-hydroxybutyric acid (GHB), and 4-methylthio-amphetamine (MTA) were assessed as more adverse than ketamine and psilocine and psilocybine-containing mushrooms. Whereas some experts slightly adjusted during the assessment procedure their opinion on ketamine and PMMA, the opinion on mushrooms was not affected by the discussion held between the two scoring rounds. All experts rank the five drugs in a similar way on the adverse effect scale i.e., concordance scale of the Electre model, indicating unanimity in the expert panel with respect to the risk classification of these abused drugs.
Type: Article
Language: en
ISSN: 0273-2300
Appears in Collections: Miscellaneous

Files in This Item:
File Description Size Format View/Open
vanamsterdam.pdf93KbAdobe PDFThumbnail

Related articles on PubMed
A Delphi technique as a method for selecting the content of an electronic patient record for asthma.
van Steenkiste BC, Jacobs JE, Verheijen NM, Levelink JH, Bottema BJ
2002 Apr
[Validation of a measurement scale: example of a French Adverse Drug Reactions Preventability Scale].
Olivier P, Caron J, Haramburu F, Imbs JL, Jonville-Béra AP, Lagier G, Sgro C, Vial T, Montastruc JL, Lapeyr-Mestre M
2005 Jan-Feb
The expert consensus guideline series. Treatment of behavioral emergencies 2005.
Allen MH, Currier GW, Carpenter D, Ross RW, Docherty JP, Expert Consensus Panel for Behavioral Emergencies 2005
2005 Nov
Use of the Delphi technique to develop standards for quality assessment in diagnostic radiology.
Stheeman SE, van 't Hof MA, Mileman PA, van der Stelt PF
1995 Dec
See all 92 articles

All Items in WARP are protected by copyright, with all rights reserved, unless otherwise indicated.