Onderzoek naar de toxiciteit van extracten van zeeslakken

2.50
Hdl Handle:
http://hdl.handle.net/10029/255513
Title:
Onderzoek naar de toxiciteit van extracten van zeeslakken
Authors:
Speijers GJA; Egmond HP van; Beenen J; Poelen MJ; Soolingen J van; Paulsch WE
Other Titles:
Investigations of the toxicity of extracts of sea-snails
Abstract:
Abstract niet beschikbaar

At the instance of the Chief Inspectorate for Health Protection, an emergency investigation was carried out, in cooperation with the State Institute for Quality Control of Agricultural Products (RIKILT), of the toxicity of sea-snails offered for consumption as whelks (Buccinum undatum). The whelks were thought to be associated with three cases of possible Paralytic Shellfish Poisoning (PSP) at Weert. The toxicity of 5 extracts, prepared and submitted to chemical analysis at the RIKILT, was tested in a mouse-bioassay according tot the official method of the Associated of Official Analytical Chemists. In one of the extracts toxicity was noticed, corresponding to ca. 35-40 mug saxitoxin- equivalents per 100 g shellfish meat. The other extracts tested in the mouse-bioassay were not lethal. The day after the toxicity experiment it became known that the suspected lot of shellfish contained "red" whelks (Neptunea antiqua) in addition to whelks. Red whelks naturally contain the poisonous substance tetramine. Consumption of these red whelks might have caused the observed intoxications. A second toxicity-experiment with mice was carried out, directed towards differences in symptoms caused by saxitoxin (one of the PSP) and the positive extract. The results of the latter experiment strengthened the assumption that tetramine rather then PSP had caused the shellfish poisoning.
Issue Date:
30-Apr-1990
URI:
http://hdl.handle.net/10029/255513
Additional Links:
http://www.rivm.nl/bibliotheek/rapporten/388802002.html; http://www.rivm.nl/bibliotheek/rapporten/388802002.pdf
Type:
Onderzoeksrapport
Language:
nl
Sponsors:
Jansen J
Appears in Collections:
RIVM official reports

Full metadata record

DC FieldValue Language
dc.contributor.authorSpeijers GJA-
dc.contributor.authorEgmond HP van-
dc.contributor.authorBeenen J-
dc.contributor.authorPoelen MJ-
dc.contributor.authorSoolingen J van-
dc.contributor.authorPaulsch WE-
dc.date.accessioned2012-12-12T12:04:13Z-
dc.date.available2012-12-12T12:04:13Z-
dc.date.issued1990-04-30-
dc.identifier388802002-
dc.identifier.urihttp://hdl.handle.net/10029/255513-
dc.description.abstractAbstract niet beschikbaarnl
dc.description.abstractAt the instance of the Chief Inspectorate for Health Protection, an emergency investigation was carried out, in cooperation with the State Institute for Quality Control of Agricultural Products (RIKILT), of the toxicity of sea-snails offered for consumption as whelks (Buccinum undatum). The whelks were thought to be associated with three cases of possible Paralytic Shellfish Poisoning (PSP) at Weert. The toxicity of 5 extracts, prepared and submitted to chemical analysis at the RIKILT, was tested in a mouse-bioassay according tot the official method of the Associated of Official Analytical Chemists. In one of the extracts toxicity was noticed, corresponding to ca. 35-40 mug saxitoxin- equivalents per 100 g shellfish meat. The other extracts tested in the mouse-bioassay were not lethal. The day after the toxicity experiment it became known that the suspected lot of shellfish contained "red" whelks (Neptunea antiqua) in addition to whelks. Red whelks naturally contain the poisonous substance tetramine. Consumption of these red whelks might have caused the observed intoxications. A second toxicity-experiment with mice was carried out, directed towards differences in symptoms caused by saxitoxin (one of the PSP) and the positive extract. The results of the latter experiment strengthened the assumption that tetramine rather then PSP had caused the shellfish poisoning.en
dc.description.sponsorshipJansen J-
dc.formatapplication/pdf-
dc.format.extent18 p-
dc.format.extent509 kb-
dc.language.isonl-
dc.relation.ispartofRIVM Rapport 388802002-
dc.relation.urlhttp://www.rivm.nl/bibliotheek/rapporten/388802002.html-
dc.relation.urlhttp://www.rivm.nl/bibliotheek/rapporten/388802002.pdf-
dc.subject07nl
dc.subjectwulkennl
dc.subjectpspnl
dc.subjectsaxitoxinenl
dc.subjectnoordhoornsnl
dc.subjecttetraminenl
dc.titleOnderzoek naar de toxiciteit van extracten van zeeslakkennl
dc.title.alternativeInvestigations of the toxicity of extracts of sea-snailsen
dc.typeOnderzoeksrapport-
dc.date.updated2012-12-12T12:04:13Z-
All Items in WARP are protected by copyright, with all rights reserved, unless otherwise indicated.