Analyse van di(2-ethylhexyl)ftalaat (DEHP) in rattevoer met hoge druk vloeistof chromatografie

2.50
Hdl Handle:
http://hdl.handle.net/10029/255813
Title:
Analyse van di(2-ethylhexyl)ftalaat (DEHP) in rattevoer met hoge druk vloeistof chromatografie
Authors:
de Fluiter P; Jansen EHJM
Other Titles:
Analysis of di(2-ethylhexyl)phthalate (DEHP) in flour with high performance liquid chromatography
Abstract:
A good, rapid and simple method has been developed to determine di(2- ethylhexyl)phthalate (DEHP) in standard flour with reversed phase high performance liquid chromatography. The method consist of an extraction as sample preparation followed by an isocratic HPLC-method in which DEHP is quantitated by use of an internal standard. The recovery of the phthalate from the flour is high (>95%). This aspect, in combination with the linearity of the calibration curve, allows an accurate determination of DEHP. The determination is very fast due to the short time of analysis: the peaks of the matrix, the internal standard and DEHP appear within 5 minutes. The developed method has been applied to samples of flour used in a toxicity study with DEHP as testcompound (TOS-TOX-90-41). The measured amounts of DEHP in the flour are in good agreement with the amounts added.<br>
Publisher:
Rijksinstituut voor Volksgezondheid en Milieu RIVM
Issue Date:
31-Oct-1991
Additional Links:
http://www.rivm.nl/bibliotheek/rapporten/618902006.html
Type:
Onderzoeksrapport
Language:
nl
Sponsors:
HIGB
Appears in Collections:
RIVM official reports

Full metadata record

DC FieldValue Language
dc.contributor.authorde Fluiter P-
dc.contributor.authorJansen EHJM-
dc.date.accessioned2014-01-17T13:46:27-
dc.date.issued1991-10-31-
dc.identifier618902006-
dc.description.abstractA good, rapid and simple method has been developed to determine di(2- ethylhexyl)phthalate (DEHP) in standard flour with reversed phase high performance liquid chromatography. The method consist of an extraction as sample preparation followed by an isocratic HPLC-method in which DEHP is quantitated by use of an internal standard. The recovery of the phthalate from the flour is high (>95%). This aspect, in combination with the linearity of the calibration curve, allows an accurate determination of DEHP. The determination is very fast due to the short time of analysis: the peaks of the matrix, the internal standard and DEHP appear within 5 minutes. The developed method has been applied to samples of flour used in a toxicity study with DEHP as testcompound (TOS-TOX-90-41). The measured amounts of DEHP in the flour are in good agreement with the amounts added.<br>en
dc.description.sponsorshipHIGB-
dc.format.extent13 p-
dc.language.isonl-
dc.publisherRijksinstituut voor Volksgezondheid en Milieu RIVM-
dc.relation.ispartofRIVM Rapport 618902006-
dc.relation.urlhttp://www.rivm.nl/bibliotheek/rapporten/618902006.html-
dc.subject18nl
dc.subject91-4nl
dc.titleAnalyse van di(2-ethylhexyl)ftalaat (DEHP) in rattevoer met hoge druk vloeistof chromatografienl
dc.title.alternativeAnalysis of di(2-ethylhexyl)phthalate (DEHP) in flour with high performance liquid chromatographyen
dc.typeOnderzoeksrapport-
dc.date.updated2014-01-17T12:48:45Z-
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