Proefbestraling van ratten met verschillende doseringen rontgenstraling t.b.v. de Granuloma Pouch Assay van het Laboratorium voor Carcinogenese en Mutagenese

2.50
Hdl Handle:
http://hdl.handle.net/10029/257620
Title:
Proefbestraling van ratten met verschillende doseringen rontgenstraling t.b.v. de Granuloma Pouch Assay van het Laboratorium voor Carcinogenese en Mutagenese
Authors:
Dijk E van; Bultman JH
Other Titles:
Test irradiations of rats with different doses X-rays for the Granuloma Pouch Assay of the Laboratory for Carcinogenesis and Mutagenesis
Abstract:
Abstract niet beschikbaar

The Laboratory of Carcinogenesis and Mutagenesis (LCM) operates a programme on Granuloma Pouch Assay. This technique is used to determine various genotoxic effects induced by radiations and for chemicals in a mesenchymal tissue (subcutaneous fibroblasts) of the rat. In the framework of this assay test experiments were performed in which 6 rats were irradiated with X-rays. The group of 6 rats was divided into three subgroups of 2 animals each, coded 1 (dose=2Gy), 2 (dose=6GY) and 3 (dose=10Gy). The purpose of these preliminary tests is to check wether the applied doses will meet further requirements for assessing the biological endpoints, the capacity involved and the experimental setup.
Issue Date:
31-Jan-1990
URI:
http://hdl.handle.net/10029/257620
Additional Links:
http://www.rivm.nl/bibliotheek/rapporten/243504002.html
Type:
Onderzoeksrapport
Language:
nl
Sponsors:
RIVM
Appears in Collections:
RIVM official reports

Full metadata record

DC FieldValue Language
dc.contributor.authorDijk E van-
dc.contributor.authorBultman JH-
dc.date.accessioned2012-12-12T15:49:29Z-
dc.date.available2012-12-12T15:49:29Z-
dc.date.issued1990-01-31-
dc.identifier243504002-
dc.identifier.urihttp://hdl.handle.net/10029/257620-
dc.description.abstractAbstract niet beschikbaarnl
dc.description.abstractThe Laboratory of Carcinogenesis and Mutagenesis (LCM) operates a programme on Granuloma Pouch Assay. This technique is used to determine various genotoxic effects induced by radiations and for chemicals in a mesenchymal tissue (subcutaneous fibroblasts) of the rat. In the framework of this assay test experiments were performed in which 6 rats were irradiated with X-rays. The group of 6 rats was divided into three subgroups of 2 animals each, coded 1 (dose=2Gy), 2 (dose=6GY) and 3 (dose=10Gy). The purpose of these preliminary tests is to check wether the applied doses will meet further requirements for assessing the biological endpoints, the capacity involved and the experimental setup.en
dc.description.sponsorshipRIVM-
dc.format.extent23 p-
dc.language.isonl-
dc.relation.ispartofRIVM Rapport 243504002-
dc.relation.urlhttp://www.rivm.nl/bibliotheek/rapporten/243504002.html-
dc.subject16nl
dc.subjectrattennl
dc.subjectratsnl
dc.subjectgranuloma pouchnl
dc.subjectbestralingnl
dc.subjectirradiationnl
dc.subjectroentgenstralingnl
dc.subjectx-raysnl
dc.titleProefbestraling van ratten met verschillende doseringen rontgenstraling t.b.v. de Granuloma Pouch Assay van het Laboratorium voor Carcinogenese en Mutagenesenl
dc.title.alternativeTest irradiations of rats with different doses X-rays for the Granuloma Pouch Assay of the Laboratory for Carcinogenesis and Mutagenesisen
dc.typeOnderzoeksrapport-
dc.date.updated2012-12-12T15:49:29Z-
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