Identification of Beta-agonists in animal samples by means of cryotrapping gas chromatography-fourier transform infrared spectrometry

2.50
Hdl Handle:
http://hdl.handle.net/10029/257660
Title:
Identification of Beta-agonists in animal samples by means of cryotrapping gas chromatography-fourier transform infrared spectrometry
Authors:
Visser T; Vredenbregt MJ; Jong APJM de; Ginkel LA van; Rossum HJ van; Stephany RW
Other Titles:
Identificatie van Beta-agonisten in dierlijk materiaal met behulp van cryotrapping gaschromatografie-Fourier transform infrarood spectrometrie.]
Abstract:
Abstract niet beschikbaar

The usefulness of cryotrapping gas chromatography-Fourier transform infrared spectrometry (GC-FTIR) for the residue analysis of the beta-agonists clenbuterol, mabuterol and salbutamol in bovine urine and tissues has been evaluated. It is demonstrated that the technique is able to detect and identify the trimethylsilyl derivatives of these compounds in urine and liver extracts of veal calves and cattle. The obtained limit of identification is approximately 1 nanogram per microliter extract injected on column which is equivalent to 2.5 microgram per liter or kilogram of the original sample. It is anticipated that the technique may develop as a valuable method for univocal confirmation of the presence of residues, particularly in addition to gas chromatography-mass spectrometry (GC-MS).
Issue Date:
31-Jan-1993
URI:
http://hdl.handle.net/10029/257660
Additional Links:
http://www.rivm.nl/bibliotheek/rapporten/388701012.html
Type:
Onderzoeksrapport
Language:
en
Sponsors:
VHI
Appears in Collections:
RIVM official reports

Full metadata record

DC FieldValue Language
dc.contributor.authorVisser T-
dc.contributor.authorVredenbregt MJ-
dc.contributor.authorJong APJM de-
dc.contributor.authorGinkel LA van-
dc.contributor.authorRossum HJ van-
dc.contributor.authorStephany RW-
dc.date.accessioned2012-12-12T15:53:46Z-
dc.date.available2012-12-12T15:53:46Z-
dc.date.issued1993-01-31-
dc.identifier388701012-
dc.identifier.urihttp://hdl.handle.net/10029/257660-
dc.description.abstractAbstract niet beschikbaarnl
dc.description.abstractThe usefulness of cryotrapping gas chromatography-Fourier transform infrared spectrometry (GC-FTIR) for the residue analysis of the beta-agonists clenbuterol, mabuterol and salbutamol in bovine urine and tissues has been evaluated. It is demonstrated that the technique is able to detect and identify the trimethylsilyl derivatives of these compounds in urine and liver extracts of veal calves and cattle. The obtained limit of identification is approximately 1 nanogram per microliter extract injected on column which is equivalent to 2.5 microgram per liter or kilogram of the original sample. It is anticipated that the technique may develop as a valuable method for univocal confirmation of the presence of residues, particularly in addition to gas chromatography-mass spectrometry (GC-MS).en
dc.description.sponsorshipVHI-
dc.format.extent18 p-
dc.language.isoen-
dc.relation.ispartofRIVM Rapport 388701012-
dc.relation.urlhttp://www.rivm.nl/bibliotheek/rapporten/388701012.html-
dc.subject18nl
dc.subjectanabolic agentsen
dc.subjectadrenergic beta-receptor agonistsen
dc.subjectresidue analyseen
dc.subjectgas chromatographyen
dc.subjectinfrared spcetrometryen
dc.subjecttissueen
dc.subjecturineen
dc.subjectanimalsen
dc.titleIdentification of Beta-agonists in animal samples by means of cryotrapping gas chromatography-fourier transform infrared spectrometryen
dc.title.alternativeIdentificatie van Beta-agonisten in dierlijk materiaal met behulp van cryotrapping gaschromatografie-Fourier transform infrarood spectrometrie.]nl
dc.typeOnderzoeksrapport-
dc.date.updated2012-12-12T15:53:51Z-
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