Novel Intervention in the Aging Population: A Primary Meningococcal Vaccine Inducing Protective IgM Responses in Middle-Aged Adults.
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Authors
van der Heiden, MariekeBoots, Annemieke M H
Bonacic Marinovic, Axel A
de Rond, Lia G H
van Maurik, Marjan
Tcherniaeva, Irina
Berbers, Guy A M
Buisman, Anne-Marie
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ArticleLanguage
en
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Novel Intervention in the Aging Population: A Primary Meningococcal Vaccine Inducing Protective IgM Responses in Middle-Aged Adults.Published in
Front Immunol 2017, 8:817Publiekssamenvatting
Vaccine responses are often reduced in the elderly, leaving part of the elderly population vulnerable to infectious diseases. Timely vaccination may offer a solution for strengthening memory immunity before reaching old age, which classifies middle-aged persons as a target age group for vaccine interventions. However, knowledge regarding the immunogenicity of primary immunizations in middle-aged adults is lacking. We determined the immunogenicity of a primary meningococcal vaccine towards which no or (very) low pre-vaccination immunity exists in middle-aged adults (NTR4636).PMID
28769927ae974a485f413a2113503eed53cd6c53
10.3389/fimmu.2017.00817
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