Use of oseltamivir in Dutch nursing homes during the 2004-2005 influenza season.

2.50
Hdl Handle:
http://hdl.handle.net/10029/6691
Title:
Use of oseltamivir in Dutch nursing homes during the 2004-2005 influenza season.
Authors:
Sande, Marianne A B van der; Ruijs, Wilhelmina L M; Meijer, Adam; Cools, Herman J M; Plas, Simone M van der
Abstract:
To assess the implementation of guidelines for using neuraminidase inhibitors in the control of influenza outbreaks in Dutch nursing homes, data were collected on prophylactic and therapeutic use of anti-viral medication, indications for use and criteria for prescribing, based on experiences during the influenza season 2004-2005 in a retrospective cross-sectional survey among Dutch nursing homes after the 2004-2005 season. Ninety/194 (49%) participating nursing homes reported an outbreak of influenza-like illness; in 57/194 (29%) influenza was laboratory confirmed. In 37/57 homes (65%) oseltamivir had been used as prophylaxis. Prophylactic use was extended to all residents and staff in 6/37 (16%) of homes, but limited in the others. In 9/37 (24%) no staff were issued prophylaxis. Among clinicians with laboratory confirmed influenza, 41/46 (89%) had used oseltamivir therapeutically. Main reasons for not prescribing oseltamivir for prophylaxis and/or therapy were lack of scientific evidence, high costs, and absent or delayed laboratory confirmation. Logistical bottlenecks in diagnosis, cost-effectiveness concerns, and lack of an evidence-base hamper full integration in policy and should be addressed.
Citation:
Vaccine 2006, 24(44-46):6664-9
Issue Date:
10-Nov-2006
URI:
http://hdl.handle.net/10029/6691
DOI:
10.1016/j.vaccine.2006.05.049
PubMed ID:
16797806
Type:
Article
Language:
en
ISSN:
0264-410X
Appears in Collections:
Vaccines and Vaccination

Full metadata record

DC FieldValue Language
dc.contributor.authorSande, Marianne A B van der-
dc.contributor.authorRuijs, Wilhelmina L M-
dc.contributor.authorMeijer, Adam-
dc.contributor.authorCools, Herman J M-
dc.contributor.authorPlas, Simone M van der-
dc.date.accessioned2006-12-21T09:18:04Z-
dc.date.available2006-12-21T09:18:04Z-
dc.date.issued2006-11-10-
dc.identifier.citationVaccine 2006, 24(44-46):6664-9en
dc.identifier.issn0264-410X-
dc.identifier.pmid16797806-
dc.identifier.doi10.1016/j.vaccine.2006.05.049-
dc.identifier.urihttp://hdl.handle.net/10029/6691-
dc.description.abstractTo assess the implementation of guidelines for using neuraminidase inhibitors in the control of influenza outbreaks in Dutch nursing homes, data were collected on prophylactic and therapeutic use of anti-viral medication, indications for use and criteria for prescribing, based on experiences during the influenza season 2004-2005 in a retrospective cross-sectional survey among Dutch nursing homes after the 2004-2005 season. Ninety/194 (49%) participating nursing homes reported an outbreak of influenza-like illness; in 57/194 (29%) influenza was laboratory confirmed. In 37/57 homes (65%) oseltamivir had been used as prophylaxis. Prophylactic use was extended to all residents and staff in 6/37 (16%) of homes, but limited in the others. In 9/37 (24%) no staff were issued prophylaxis. Among clinicians with laboratory confirmed influenza, 41/46 (89%) had used oseltamivir therapeutically. Main reasons for not prescribing oseltamivir for prophylaxis and/or therapy were lack of scientific evidence, high costs, and absent or delayed laboratory confirmation. Logistical bottlenecks in diagnosis, cost-effectiveness concerns, and lack of an evidence-base hamper full integration in policy and should be addressed.en
dc.format.extent124439 bytes-
dc.format.mimetypeapplication/pdf-
dc.language.isoenen
dc.titleUse of oseltamivir in Dutch nursing homes during the 2004-2005 influenza season.en
dc.typeArticleen
dc.format.digYES-

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