2.50
Hdl Handle:
http://hdl.handle.net/10029/7166
Title:
Brain stem and cerebellar hyperintense lesions in migraine.
Authors:
Kruit, Mark C; Launer, Lenore J; Ferrari, Michel D; Buchem, Mark A van
Abstract:
BACKGROUND AND PURPOSE: Migraineurs are at increased risk of cerebellar infarcts and supratentorial white matter lesions. The prevalence, frequency, and distribution of infratentorial hyperintense lesions in migraine are unknown. METHODS: Migraineurs with aura (n=161), without aura (n=134), and controls (n=140) from a population-based sample of adults (30 to 60 years of age) were evaluated with MRI. RESULTS: Infratentorial hyperintensities were identified in 13 of 295 (4.4%) migraineurs and in 1 of 140 (0.7%) controls (P=0.04). Twelve cases had hyperintensities, mostly bilaterally, in the dorsal basis pontis. Those with infratentorial hyperintensities also had supratentorial white matter lesions more often. CONCLUSIONS: We found an increased prevalence of infratentorial (mostly pontine) hyperintensities in migraineurs from the general population. This extends the knowledge about vulnerable brain regions and type of lesions in migraine brains. A hemodynamic ischemic pathogenesis is likely, but further research is needed.
Citation:
Stroke 2006, 37(4):1109-12
Issue Date:
1-Apr-2006
URI:
http://hdl.handle.net/10029/7166
DOI:
10.1161/01.STR.0000206446.26702.e9
PubMed ID:
16497982
Type:
Article
Language:
en
ISSN:
1524-4628
Appears in Collections:
Public Health and Health Care

Full metadata record

DC FieldValue Language
dc.contributor.authorKruit, Mark C-
dc.contributor.authorLauner, Lenore J-
dc.contributor.authorFerrari, Michel D-
dc.contributor.authorBuchem, Mark A van-
dc.date.accessioned2007-01-10T11:06:27Z-
dc.date.available2007-01-10T11:06:27Z-
dc.date.issued2006-04-01-
dc.identifier.citationStroke 2006, 37(4):1109-12en
dc.identifier.issn1524-4628-
dc.identifier.pmid16497982-
dc.identifier.doi10.1161/01.STR.0000206446.26702.e9-
dc.identifier.urihttp://hdl.handle.net/10029/7166-
dc.description.abstractBACKGROUND AND PURPOSE: Migraineurs are at increased risk of cerebellar infarcts and supratentorial white matter lesions. The prevalence, frequency, and distribution of infratentorial hyperintense lesions in migraine are unknown. METHODS: Migraineurs with aura (n=161), without aura (n=134), and controls (n=140) from a population-based sample of adults (30 to 60 years of age) were evaluated with MRI. RESULTS: Infratentorial hyperintensities were identified in 13 of 295 (4.4%) migraineurs and in 1 of 140 (0.7%) controls (P=0.04). Twelve cases had hyperintensities, mostly bilaterally, in the dorsal basis pontis. Those with infratentorial hyperintensities also had supratentorial white matter lesions more often. CONCLUSIONS: We found an increased prevalence of infratentorial (mostly pontine) hyperintensities in migraineurs from the general population. This extends the knowledge about vulnerable brain regions and type of lesions in migraine brains. A hemodynamic ischemic pathogenesis is likely, but further research is needed.en
dc.format.extent261550 bytes-
dc.format.mimetypeapplication/pdf-
dc.language.isoenen
dc.titleBrain stem and cerebellar hyperintense lesions in migraine.en
dc.typeArticleen
dc.format.digYES-

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