Rapportage 'Effecten van luchtverontreiniging op allergie'. Basisschool Onderzoek Luchtverontreiniging en Allergie (BOLA)

2.50
Hdl Handle:
http://hdl.handle.net/10029/9265
Title:
Rapportage 'Effecten van luchtverontreiniging op allergie'. Basisschool Onderzoek Luchtverontreiniging en Allergie (BOLA)
Authors:
Steerenberg PA; Bischoff EWMA; Klerk A de; Verlaan APJ; Jongbloets LMN; Loveren H van; Opperhuizen A; Zomer G; Heisterkamp SH; Hady M; Spieksma FTM; Fischer PH; Dormans JAMA; Amsterdam JGC
Other Titles:
Report 'Effects of air pollution on allergy'
Abstract:
In the last decade the prevalence of asthma and allergy is increasing. Epidemiological studies have frequently shown that allergic diseases and asthma are more prevalent in children living in areas with relative high traffic intensity. To study whether the urban air pollution adversely affects the allergic responses to pollen and house dust mite, the present study was performed in allergic and non-allergic children living in the city of Utrecht (Zuilen and Ondiep). 119 Schoolchildren were selected and they were divided into 4 groups: children without allergy, and children allergic for pollen, for house dust mite or for both pollen and house dust mite. Besides the completing a diary, the higher and lower respiratory tract of children were investigated using non-invasive sampling procedures. The results show that the levels of air pollution in the region Zuilen/Ondiep, measured in the study, are normal for urban regions and below the current standards. Between the groups with different ethnic origin differences in prevalence of allergic sensitisation were observed. Children sensitised to pollen, house dust mite or to both allergens, do not show an increased prevalence of complaints during exposure to pollen or increased levels of airpollution. This is objectified by the results obtained in the study measuring biomarkers in exhaled air and nasal lavage. In conclusion, children allergic for airway-allergens (based on positive skin test) have significant more respiratory complaints than children who were negative in this test. However, during this study air pollution did neither facilitate a stronger allergic reaction nor did it result in more respiratory complaints in school children living in the regions Zuilen and Ondiep.
Other Contributors:
Gemeentelijke Geneeskundige- en Gezondheidsdienst, Utrecht, Afdeling Longziekten; Leids Universitair Medisch Centrum, Leiden
Affiliation:
TOX
Publisher:
Rijksinstituut voor Volksgezondheid en Milieu RIVM
Issue Date:
5-Jun-2003
URI:
http://hdl.handle.net/10029/9265
Additional Links:
http://www.rivm.nl/bibliotheek/rapporten/640250007.html
Language:
nl
Series/Report no.:
RIVM rapport 640250007
Appears in Collections:
RIVM reports - old archive

Full metadata record

DC FieldValue Language
dc.contributor.authorSteerenberg PAen_US
dc.contributor.authorBischoff EWMAen_US
dc.contributor.authorKlerk A deen_US
dc.contributor.authorVerlaan APJen_US
dc.contributor.authorJongbloets LMNen_US
dc.contributor.authorLoveren H vanen_US
dc.contributor.authorOpperhuizen Aen_US
dc.contributor.authorZomer Gen_US
dc.contributor.authorHeisterkamp SHen_US
dc.contributor.authorHady Men_US
dc.contributor.authorSpieksma FTMen_US
dc.contributor.authorFischer PHen_US
dc.contributor.authorDormans JAMAen_US
dc.contributor.authorAmsterdam JGCen_US
dc.contributor.otherGemeentelijke Geneeskundige- en Gezondheidsdienst, Utrecht, Afdeling Longziektenen_US
dc.contributor.otherLeids Universitair Medisch Centrum, Leidenen_US
dc.date.accessioned2007-02-26T16:13:42Z-
dc.date.available2007-02-26T16:13:42Z-
dc.date.issued2003-06-05en_US
dc.identifier640250007en_US
dc.identifier.urihttp://hdl.handle.net/10029/9265-
dc.description.abstractIn the last decade the prevalence of asthma and allergy is increasing. Epidemiological studies have frequently shown that allergic diseases and asthma are more prevalent in children living in areas with relative high traffic intensity. To study whether the urban air pollution adversely affects the allergic responses to pollen and house dust mite, the present study was performed in allergic and non-allergic children living in the city of Utrecht (Zuilen and Ondiep). 119 Schoolchildren were selected and they were divided into 4 groups: children without allergy, and children allergic for pollen, for house dust mite or for both pollen and house dust mite. Besides the completing a diary, the higher and lower respiratory tract of children were investigated using non-invasive sampling procedures. The results show that the levels of air pollution in the region Zuilen/Ondiep, measured in the study, are normal for urban regions and below the current standards. Between the groups with different ethnic origin differences in prevalence of allergic sensitisation were observed. Children sensitised to pollen, house dust mite or to both allergens, do not show an increased prevalence of complaints during exposure to pollen or increased levels of airpollution. This is objectified by the results obtained in the study measuring biomarkers in exhaled air and nasal lavage. In conclusion, children allergic for airway-allergens (based on positive skin test) have significant more respiratory complaints than children who were negative in this test. However, during this study air pollution did neither facilitate a stronger allergic reaction nor did it result in more respiratory complaints in school children living in the regions Zuilen and Ondiep.en
dc.format.extent486000 bytesen_US
dc.format.extent497563 bytes-
dc.format.mimetypeapplication/pdf-
dc.language.isonlen_US
dc.publisherRijksinstituut voor Volksgezondheid en Milieu RIVMen_US
dc.relation.ispartofseriesRIVM rapport 640250007en_US
dc.relation.urlhttp://www.rivm.nl/bibliotheek/rapporten/640250007.htmlen_US
dc.subject.otherair pollutionen
dc.subject.otherallergyen
dc.subject.otherasthmaen
dc.subject.otherbiomarkersen
dc.subject.otherurban areasen
dc.subject.otherchildrenen
dc.subject.otherluchtverontreinigingnl
dc.subject.otherallergienl
dc.subject.otherastmanl
dc.subject.otherbiomarkersnl
dc.subject.otherstedelijke omgevingnl
dc.subject.otherkinderennl
dc.titleRapportage 'Effecten van luchtverontreiniging op allergie'. Basisschool Onderzoek Luchtverontreiniging en Allergie (BOLA)en_US
dc.title.alternativeReport 'Effects of air pollution on allergy'en_US
dc.contributor.departmentTOXen_US
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