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Establishing a Quantitative Framework for Regulatory Interpretation of Genetic Toxicity Dose-Response Data: MOE (Margin of Exposure) Case Study of 48 Compounds with both in vivo Mutagenicity and Carcinogenicity Dose-Response Data.

Chepelev, Nikolai
Long, Alexandra S
Beal, Marc
Barton-Maclaren, Tara
Johnson, George
Dearfield, Kerry L
Roberts, Daniel J
van Benthem, Jan
White, Paul
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Article
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en
Date of publication
2022-11-08
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Title
Establishing a Quantitative Framework for Regulatory Interpretation of Genetic Toxicity Dose-Response Data: MOE (Margin of Exposure) Case Study of 48 Compounds with both in vivo Mutagenicity and Carcinogenicity Dose-Response Data.
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Environ Mol Mutagen 2023; 64(1):4-15
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