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An overview of the available data on reproduction toxicity of 4-nonylphenol
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Series / Report no.
RIVM rapport 2022-0022
Open Access
Type
Report
Language
en
Date
2022-03-28
Research Projects
Organizational Units
Journal Issue
Title
An overview of the available data on reproduction toxicity of 4-nonylphenol
Translated Title
4-Nonylfenol: overzicht van de beschikbare informatie over reproductietoxiciteit
Published in
Abstract
De stof 4-nonylfenol wordt gebruikt bij de productie van nonylfenolethoxylaten. Deze stoffen zitten in verf, schoonmaakmiddelen en gewasbeschermingsmiddelen.
Het RIVM heeft in de wetenschappelijke literatuur onderzocht wat er bekend is over schadelijke effecten van 4-nonylfenol op de voortplanting.
Het RIVM deed dat in opdracht van de Gezondheidsraad. De Gezondheidsraad gaat een voorstel doen om de stof in een bepaalde ‘gevaarsklasse’ in te delen. Als voorbereiding daarop gebruikt de Gezondheidsraad het overzicht van het RIVM om te beoordelen of 4-nonylfenol schadelijk is voor de voortplanting. De minister van Sociale Zaken en Werkgelegenheid (SZW) heeft om dit advies gevraagd.
Het RIVM heeft zes studies over effecten van de stof op de voortplanting bij dieren gevonden. De gevonden informatie is samengevat.
4-Nonylphenol is a substance that is being used to produce nonylphenol ethoxylates. These substances are used in paints, detergents and plant protection products. At the request of the Health Council, RIVM has conducted literature research on the potential effects of 4-nonylphenol on reproduction. The Health Council will provide a recommendation for the hazard classification of 4-nonylphenol. As a starting point, the Health Council will use this literature research for an independent evaluation of the reproduction toxic properties of 4-nonylphenol, as requested by the Minister for Social Affairs and Employment. With respect to reproduction toxicity endpoints, the literature research yielded six studies on the reproduction toxic properties of 4-nonylphenol in animals. The retrieved information was summarized.
4-Nonylphenol is a substance that is being used to produce nonylphenol ethoxylates. These substances are used in paints, detergents and plant protection products. At the request of the Health Council, RIVM has conducted literature research on the potential effects of 4-nonylphenol on reproduction. The Health Council will provide a recommendation for the hazard classification of 4-nonylphenol. As a starting point, the Health Council will use this literature research for an independent evaluation of the reproduction toxic properties of 4-nonylphenol, as requested by the Minister for Social Affairs and Employment. With respect to reproduction toxicity endpoints, the literature research yielded six studies on the reproduction toxic properties of 4-nonylphenol in animals. The retrieved information was summarized.
Description
Publisher
Rijksinstituut voor Volksgezondheid en Milieu RIVM