Detection and identification of "new" beta-agonists in black-market preparations
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Series / Report no.
Open Access
Type
Report
Language
en
Date
1992-02-29
Research Projects
Organizational Units
Journal Issue
Title
Detection and identification of "new" beta-agonists in black-market preparations
Translated Title
Detectie en identificatie van "nieuwe" beta-agonisten in preparaten afkomstig van de zwarte markt
Published in
Abstract
In several "black-market" used for growth promotion preparations new compounds were found belonging to the group of N-phenylethanolamines with structures very similar to compounds known to be used for veal calf and cattle production, the so called beta-agonists. The two most important compounds are "mapenterol", closely related to mabuterol and "cimbuterol", closely related to cimaterol. Each time the "new" compound differs in the aliphatic moiety of the molecule in that one H-atom is substituted for a methyl group. Confirmation of the identity of the structures is based on their low resolution mass spectra, behaviour in the analytical system and in part on the NMR- and FTIR spectra. Moreover, identical compiunds were found by other Benelux-research institutes. The compounds are currently being synthesized.<br>
Description
Publisher
Rijksinstituut voor Volksgezondheid en Milieu RIVM
Sponsors
VHI