Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes.
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Series / Report no.
Open Access
Type
Article
Language
en
Date
2017-06-01
Research Projects
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Journal Issue
Title
Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes.
Translated Title
Published in
Am J Resp Crit Care Med 2017; 195(11):1519-27
Abstract
Successful transmission of tuberculosis depends on the interplay of human behavior, host immune responses, and Mycobacterium tuberculosis virulence factors. Previous studies have been focused on identifying host risk factors associated with increased transmission, but the contribution of specific genetic variations in mycobacterial strains themselves are still unknown.