Silica encapsulation of ZnO nanoparticles reduces their toxicity for cumulus cell-oocyte-complex expansion.
Camaioni, Antonella Massimiani, Micol Lacconi, Valentina Magrini, Andrea Salustri, Antonietta Sotiriou, Georgios A Singh, Dilpreet Bitounis, Dimitrios Bocca, Beatrice Pino, Anna
Camaioni, Antonella
Massimiani, Micol
Lacconi, Valentina
Magrini, Andrea
Salustri, Antonietta
Sotiriou, Georgios A
Singh, Dilpreet
Bitounis, Dimitrios
Bocca, Beatrice
Pino, Anna
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Series / Report no.
Open Access
Type
Article
Language
en
Date of publication
2021-09-03
Year of publication
Research Projects
Organizational Units
Journal Issue
Title
Silica encapsulation of ZnO nanoparticles reduces their toxicity for cumulus cell-oocyte-complex expansion.
Translated Title
Published in
Part Fibre Toxicol 2021; 18(1):33
Abstract
Mouse COCs from pre-ovulatory follicles were cultured in vitro in the presence of various concentrations of two types of TiO2 NPs (JRC NM-103 and NM-104) and four types of ZnO NPs (JRC NM-110, NM-111, and in-house prepared uncoated and SiO2-coated NPs) and the organization of a muco-elastic extracellular matrix by cumulus cells during the process named cumulus expansion was investigated.