Silica encapsulation of ZnO nanoparticles reduces their toxicity for cumulus cell-oocyte-complex expansion.
Camaioni, Antonella; Massimiani, Micol; Lacconi, Valentina; Magrini, Andrea; Salustri, Antonietta; Sotiriou, Georgios A; Singh, Dilpreet; Bitounis, Dimitrios; Bocca, Beatrice; Pino, Anna; Barone, Flavia; Prota, Valentina; Iavicoli, Ivo; Scimeca, Manuel; Bonanno, Elena; Cassee, Flemming R; Demokritou, Philip; Pietroiusti, Antonio; Campagnolo, Luisa
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Open Access
Type
Article
Language
en
Date
2021-09-03
Research Projects
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Title
Silica encapsulation of ZnO nanoparticles reduces their toxicity for cumulus cell-oocyte-complex expansion.
Translated Title
Published in
Part Fibre Toxicol 2021; 18(1):33
Abstract
Mouse COCs from pre-ovulatory follicles were cultured in vitro in the presence of various concentrations of two types of TiO2 NPs (JRC NM-103 and NM-104) and four types of ZnO NPs (JRC NM-110, NM-111, and in-house prepared uncoated and SiO2-coated NPs) and the organization of a muco-elastic extracellular matrix by cumulus cells during the process named cumulus expansion was investigated.