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First detection and autochthonous transmission of monkeypox virus clade Ib in the Netherlands, October to November, 2025

Elsinga, Jelte
van de Ven, Celine
de Vries, Anne
Coppoolse, Hester
Petrignani, Mariska
van Cleef, Brigitte
van Markus, Riemer
Carpay, Nora
van Ewijk, Catharina E
Rebers, Sjoerd
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Journal Article
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Language
en
Date of publication
2026-01
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Title
First detection and autochthonous transmission of monkeypox virus clade Ib in the Netherlands, October to November, 2025
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Euro Surveill 2026; 31(3)
Abstract
In October-November 2025, eight autochthonous cases of monkeypox (MPXV) clade Ib virus infection were reported in the Netherlands. All cases were men who have sex with men aged 25-65; none required hospital admission or antiviral treatment. Phylogenetic analysis combined with contact tracing suggest multiple introductions or cryptic circulation with onwards transmission within the community. Highly related international sequences were identified dating back to August 2025, indicating sustained global community transmission of clade Ib outside the African continent.
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