Protein and amino acid intakes in relation to prostate cancer risk and mortality-A prospective study in the European Prospective Investigation into Cancer and Nutrition.
Schmidt, Julie A; Huybrechts, Inge; Overvad, Kim; Eriksen, Anne Kirstine; Tjønneland, Anne; Kaaks, Rudolf; Katzke, Verena; Schulze, Matthias B; Pala, Valeria; Sacerdote, Carlotta; Tumino, Rosario; Bueno-de-Mesquita, Bas; Sánchez, Maria-Jose; Huerta, José M; Barricarte, Aurelio; Amiano, Pilar; Agudo, Antonio; Bjartell, Anders; Stocks, Tanja; Thysell, Elin; Wennberg, Maria; Weiderpass, Elisabete; Travis, Ruth C; Key, Timothy J; Perez-Cornago, Aurora
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Open Access
Type
Article
Language
en
Date
2022-09-23
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Title
Protein and amino acid intakes in relation to prostate cancer risk and mortality-A prospective study in the European Prospective Investigation into Cancer and Nutrition.
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Cancer Med 2023;12(4):4725-4738
Abstract
During a mean follow-up of 14.2 years, 6939 men were diagnosed with prostate cancer and 914 died of the disease. Dairy protein was positively associated with overall prostate cancer risk in the three highest fifths compared to the lowest (HRQ3 =1.14 (95% CI 1.05-1.23); HRQ 4=1.09 (1.01-1.18); HRQ5 =1.10 (1.02-1.19)); similar results were observed for yogurt protein (HRQ3 =1.14 (1.05-1.24); HRQ4 =1.09 (1.01-1.18); HRQ5 =1.12 (1.04-1.21)). For egg protein intake and prostate cancer mortality, no association was observed by fifths, but there was suggestive evidence of a positive association in the analysis per standard deviation increment. There was no strong evidence of associations with different tumour subtypes.