Overcoming scientific barriers in the transition from to non-animal batch testing of human and veterinary vaccines.
Citations
Altmetric:
Series / Report no.
Open Access
Type
Article
Language
en
Date
2021-09-22
Research Projects
Organizational Units
Journal Issue
Title
Overcoming scientific barriers in the transition from to non-animal batch testing of human and veterinary vaccines.
Translated Title
Published in
Expert Rev Vaccines 2021; 20(13):1221-1233
Abstract
Before release, vaccine batches are assessed for quality to evaluate whether they meet the product specifications. Vaccine batch tests, in particular of inactivated and toxoid vaccines, still largely rely on in vivo methods. Improved vaccine production processes, ethical concerns, and suboptimal performance of some in vivo tests have led to the development of in vitro alternatives.