Mutagene stoffen en risico's voor natuurlijke populaties. Onderzoek met Daphnia magna als modelorganisme. II. Experimenten met een mutagene stof
Vaal MA Breedijk I Dekker MP Mout HCA Kramers PGN Roghair CJ
Vaal MA
Breedijk I
Dekker MP
Mout HCA
Kramers PGN
Roghair CJ
Citations
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Series / Report no.
Open Access
Type
Report
Language
nl
Date of publication
1992-12-31
Year of publication
Research Projects
Organizational Units
Journal Issue
Title
Mutagene stoffen en risico's voor natuurlijke populaties. Onderzoek met Daphnia magna als modelorganisme. II. Experimenten met een mutagene stof
Translated Title
[Mutagenic substances and natural populations at risk. Research with Daphnia magna as a model organism. II. Experiments with a mutagenic substance.]
Published in
Abstract
Daphnia magna is used as a model organism to study the consequences of the impact of mutagenic chemicals to natural populations. Adult daphnids were exposed to a mutagenic test compound to test whether their offspring showed effects of induced mutations at exposure levels lower than the No Observed Effect Concentration for growth and reproduction. Life-history parameters were used as test parameters. A concentration-related toxic effect to reproduction could be measured reproducibly in the exposed adult daphnids. However, no indication of a mutagenic effect could be detected in their offspring. This may have been due to the inadequateness of the system to detect induced genetic change.<br>
Description
Publisher
Rijksinstituut voor Volksgezondheid en Milieu RIVM
Sponsors
DGM/SVS
STIMTOX
STIMTOX