Mutagene stoffen en risico's voor natuurlijke populaties. Onderzoek met Daphnia magna als modelorganisme. II. Experimenten met een mutagene stof
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Series / Report no.
Open Access
Type
Report
Language
nl
Date
1992-12-31
Research Projects
Organizational Units
Journal Issue
Title
Mutagene stoffen en risico's voor natuurlijke populaties. Onderzoek met Daphnia magna als modelorganisme. II. Experimenten met een mutagene stof
Translated Title
[Mutagenic substances and natural populations at risk. Research with Daphnia magna as a model organism. II. Experiments with a mutagenic substance.]
Published in
Abstract
Daphnia magna is used as a model organism to study the consequences of the impact of mutagenic chemicals to natural populations. Adult daphnids were exposed to a mutagenic test compound to test whether their offspring showed effects of induced mutations at exposure levels lower than the No Observed Effect Concentration for growth and reproduction. Life-history parameters were used as test parameters. A concentration-related toxic effect to reproduction could be measured reproducibly in the exposed adult daphnids. However, no indication of a mutagenic effect could be detected in their offspring. This may have been due to the inadequateness of the system to detect induced genetic change.<br>
Description
Publisher
Rijksinstituut voor Volksgezondheid en Milieu RIVM
Sponsors
DGM/SVS
STIMTOX
STIMTOX