Rapid cross-border emergence of NDM-5-producing in the European Union/European Economic Area, 2012 to June 2022.
Linkevicius, Marius Bonnin, Rémy A Alm, Erik Svartström, Olov Apfalter, Petra Hartl, Rainer Hasman, Henrik Roer, Louise Räisänen, Kati Dortet, Laurent
Linkevicius, Marius
Bonnin, Rémy A
Alm, Erik
Svartström, Olov
Apfalter, Petra
Hartl, Rainer
Hasman, Henrik
Roer, Louise
Räisänen, Kati
Dortet, Laurent
Research Projects
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Journal Issue
Title
Rapid cross-border emergence of NDM-5-producing in the European Union/European Economic Area, 2012 to June 2022.
Translated Title
Published in
Euro Surveill 2023;28(19):2300209
Abstract
Whole genome sequencing data of 874 Escherichia coli isolates carrying bla NDM-5 from 13 European Union/European Economic Area countries between 2012 and June 2022 showed the predominance of sequence types ST167, ST405, ST410, ST361 and ST648, and an increasing frequency of detection. Nearly a third (30.6%) of these isolates were associated with infections and more than half (58.2%) were predicted to be multidrug-resistant. Further spread of E. coli carrying bla NDM-5 would leave limited treatment options for serious E. coli infections.