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Population-level impact, herd immunity, and elimination after human papillomavirus vaccination: a systematic review and meta-analysis of predictions from transmission-dynamic models.
Brisson, Marc Bénard, Élodie Drolet, Mélanie Bogaards, Johannes A Baussano, Iacopo Vänskä, Simopekka Jit, Mark Boily, Marie-Claude Smith, Megan A Berkhof, Johannes
Brisson, Marc
Bénard, Élodie
Drolet, Mélanie
Bogaards, Johannes A
Baussano, Iacopo
Vänskä, Simopekka
Jit, Mark
Boily, Marie-Claude
Smith, Megan A
Berkhof, Johannes
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Open Access
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Article
Language
en
Date of publication
2016-11
Year of publication
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Title
Population-level impact, herd immunity, and elimination after human papillomavirus vaccination: a systematic review and meta-analysis of predictions from transmission-dynamic models.
Translated Title
Published in
Lancet Public Health 2016; 1(1):e8-17
Abstract
Modelling studies have been widely used to inform human papillomavirus (HPV) vaccination policy decisions; however, many models exist and it is not known whether they produce consistent predictions of population-level effectiveness and herd effects. We did a systematic review and meta-analysis of model predictions of the long-term population-level effectiveness of vaccination against HPV 16, 18, 6, and 11 infection in women and men, to examine the variability in predicted herd effects, incremental benefit of vaccinating boys, and potential for HPV-vaccine-type elimination.