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Clinical implications of airway obstruction with normal or low FEV1 in childhood and adolescence

Koefoed, Hans Jacob Lohne
Wang, Gang
Gehring, Ulrike
Ekstrom, Sandra
Kull, Inger
Vermeulen, Roel
Boer, Jolanda MA
Bergstrom, Anna
Koppelman, Gerard H
Melén, Erik
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Article
Language
en
Date of publication
2024-05-20
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Title
Clinical implications of airway obstruction with normal or low FEV1 in childhood and adolescence
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Thorax 2024;79(6):573-580
Abstract
Airway obstruction is defined by spirometry as a low forced expiratory volume in 1 s (FEV1) to forced vital capacity (FVC) ratio. This impaired ratio may originate from a low FEV1 (classic) or a normal FEV1 in combination with a large FVC (dysanaptic). The clinical implications of dysanaptic obstruction during childhood and adolescence in the general population remain unclear.
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