Factors associated with high oxidative stress in patients with type 2 diabetes: a meta-analysis of two cohort studies.
Anusruti, Ankita Xuan, Yang Gào, Xīn Jansen, Eugène H J M Laetsch, Dana Clarissa Brenner, Hermann Schöttker, Ben
Anusruti, Ankita
Xuan, Yang
Gào, Xīn
Jansen, Eugène H J M
Laetsch, Dana Clarissa
Brenner, Hermann
Schöttker, Ben
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Open Access
Type
Article
Language
en
Date of publication
2020-01-01
Year of publication
Research Projects
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Title
Factors associated with high oxidative stress in patients with type 2 diabetes: a meta-analysis of two cohort studies.
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Published in
BMJ Open Diabetes Res Care 2020; 8(1):e000933
Abstract
In the meta-analysis of the cross-sectional analysis, female sex, low education, obesity, smoking, high total cholesterol, hemoglobin A1c ≥7%, no diabetes medication, a history of myocardial infarction, heart failure, a history of cancer and C reactive protein levels (CRP) >3 mg/L were statistically significantly associated with increased D-ROM levels in patients with T2DM. The meta-analysis of the longitudinal analysis revealed that old age, female sex, obesity, smoking, physical inactivity, high alcohol consumption, ≥5 years since diabetes diagnosis and CRP levels between 3 mg/L and 10 mg/L were statistically significantly associated with D-ROM levels measured 3-4 years later.