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Induction of salivary antibody levels in Dutch adolescents after immunization with monovalent meningococcal serogroup C or quadrivalent meningococcal serogroup A, C, W and Y conjugate vaccine.
van Ravenhorst, Mariëtte B den Hartog, Gerco van der Klis, Fiona R M van Rooijen, Debbie M Sanders, Elisabeth A M Berbers, Guy A M
van Ravenhorst, Mariëtte B
den Hartog, Gerco
van der Klis, Fiona R M
van Rooijen, Debbie M
Sanders, Elisabeth A M
Berbers, Guy A M
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Open Access
Type
Article
Language
en
Date of publication
2018
Year of publication
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2018236.pdf
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Title
Induction of salivary antibody levels in Dutch adolescents after immunization with monovalent meningococcal serogroup C or quadrivalent meningococcal serogroup A, C, W and Y conjugate vaccine.
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Published in
Plos One 2018; 13(4):e0191261
Abstract
Meningococcal infection starts with colonisation of the upper respiratory tract. Mucosal immunity is important for protection against acquisition and subsequent meningococcal carriage. In this study, we assessed salivary antibody levels against meningococcal serogroup A (MenA), W (MenW) and Y (MenY) after vaccination with a quadrivalent MenACWY conjugated vaccine. We also compared salivary meningococcal serogroup C (MenC) antibody levels after monovalent MenC and quadrivalent MenACWY conjugated vaccination.