Anti-Müllerian hormone levels and risk of type 2 diabetes in women.
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Open Access
Type
Article
Language
en
Date
2020-10-13
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Journal Issue
Title
Anti-Müllerian hormone levels and risk of type 2 diabetes in women.
Translated Title
Published in
Diabetologia 2020; advance online publication (ahead of print)
Abstract
During a median follow-up of 20 years, 163 women developed type 2 diabetes. Lower baseline age-specific AMH levels were associated with a higher type 2 diabetes risk (HRT2vsT3 1.24 [95% CI 0.81, 1.92]; HRT1vsT3 1.62 [95% CI 1.06, 2.48]; ptrend = 0.02). These findings seem to be supported by predicted AMH trajectories, which suggested that plasma AMH levels were lower at younger ages in women who developed type 2 diabetes compared with women who did not. The trajectories also suggested that AMH levels declined at a slower rate in women who developed type 2 diabetes, although differences in trajectories were not statistically significant.