Impact and cost-effectiveness of different vaccination strategies to reduce the burden of pneumococcal disease among elderly in the Netherlands.
Thorrington, Dominic van Rossum, Leo Knol, Mirjam de Melker, Hester Rümke, Hans Hak, Eelko van Hoek, Albert Jan
Thorrington, Dominic
van Rossum, Leo
Knol, Mirjam
de Melker, Hester
Rümke, Hans
Hak, Eelko
van Hoek, Albert Jan
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Series / Report no.
Open Access
Type
Article
Language
en
Date of publication
2018
Year of publication
Research Projects
Organizational Units
Journal Issue
Title
Impact and cost-effectiveness of different vaccination strategies to reduce the burden of pneumococcal disease among elderly in the Netherlands.
Translated Title
Published in
Plos One 2018; 13(2):e0192640
Abstract
Streptococcus pneumoniae causes morbidity and mortality among all ages in The Netherlands. To reduce this burden, infants in The Netherlands receive the 10-valent pneumococcal conjugated vaccine (PCV10), but older persons are not targeted. We assessed the impact and cost-effectiveness of vaccination with 23-valent pneumococcal polysaccharide vaccine (PPV23) or 13-valent PCV (PCV13) among all those aged 60, 65 or 70 and/or in combination with replacing PCV10 with PCV13 in the infant vaccination programme.