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Use of the kinetically-derived maximum dose concept in selection of top doses for toxicity studies hampers proper hazard assessment and risk management.

Heringa, Minne B
Cnubben, Nicole H P
Slob, Wout
Pronk, Marja E J
Muller, Andre
Woutersen, Marjolijn
Hakkert, Betty C
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Article
Language
en
Date of publication
2020-07-01
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Title
Use of the kinetically-derived maximum dose concept in selection of top doses for toxicity studies hampers proper hazard assessment and risk management.
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Regul Toxicol Pharmacol 2020; 114:104659
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