Physical activity, mediating factors and risk of colon cancer: insights into adiposity and circulating biomarkers from the EPIC cohort.
Aleksandrova, Krasimira Jenab, Mazda Leitzmann, Michael Bueno-de-Mesquita, Bas Kaaks, Rudolf Trichopoulou, Antonia Bamia, Christina Lagiou, Pagona Rinaldi, Sabina Freisling, Heinz
Aleksandrova, Krasimira
Jenab, Mazda
Leitzmann, Michael
Bueno-de-Mesquita, Bas
Kaaks, Rudolf
Trichopoulou, Antonia
Bamia, Christina
Lagiou, Pagona
Rinaldi, Sabina
Freisling, Heinz
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Series / Report no.
Open Access
Type
Article
Language
en
Date of publication
2017-12-01
Year of publication
Research Projects
Organizational Units
Journal Issue
Title
Physical activity, mediating factors and risk of colon cancer: insights into adiposity and circulating biomarkers from the EPIC cohort.
Translated Title
Published in
Int J Epidemiol 2017; 46(6):1823-35
Abstract
There is convincing evidence that high physical activity lowers the risk of colon cancer; however, the underlying biological mechanisms remain largely unknown. We aimed to determine the extent to which body fatness and biomarkers of various biologically plausible pathways account for the association between physical activity and colon cancer.