Bepaling van de beta-adrenerge bindingskarakteristiek in humane- en rattelymphocyten
van Amsterdam JGC Eigeman L Wemer J de Wildt DJ
van Amsterdam JGC
Eigeman L
Wemer J
de Wildt DJ
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Series / Report no.
Open Access
Type
Report
Language
nl
Date of publication
1994-01-31
Year of publication
Research Projects
Organizational Units
Journal Issue
Title
Bepaling van de beta-adrenerge bindingskarakteristiek in humane- en rattelymphocyten
Translated Title
[Assay of beta-adrenergic bindingcharacteristics in human-and rat lymphocytes.]
Published in
Abstract
Bindingcharacteristics of beta-adrenergic receptors were assayed in membranes of human-and rat lymphocytes using iodocyanopindolol (ICYP) as radioactive labelled ligand. The affinity constant (Kd) of ICYP for human and rat adrenergic receptors was respectively 8.5 and 16.5 pM. Total number of receptors (Bmax) in the species studied were respectively 70 and 160 fmole/mg protein.<br>
Description
Publisher
Rijksinstituut voor Volksgezondheid en Milieu RIVM
Sponsors
RIVM