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Detection of titanium particles in human liver and spleen and possible health implications.
Heringa, M B Peters, R J B Bleys, R L A W van der Lee, M K Tromp, P C van Kesteren, P C E van Eijkeren, J C H Undas, A K Oomen, A G Bouwmeester, H
Heringa, M B
Peters, R J B
Bleys, R L A W
van der Lee, M K
Tromp, P C
van Kesteren, P C E
van Eijkeren, J C H
Undas, A K
Oomen, A G
Bouwmeester, H
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Series / Report no.
Open Access
Type
Article
Language
en
Date of publication
2018-04-11
Year of publication
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s12989-018-0251-7.pdf
Adobe PDF, 1.05 MB
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Title
Detection of titanium particles in human liver and spleen and possible health implications.
Translated Title
Published in
Part Fibre Toxicol 2018; 15(1):15
Abstract
Titanium dioxide (TiO2) is produced at high volumes and applied in many consumer and food products. Recent toxicokinetic modelling indicated the potential of TiO2 to accumulate in human liver and spleen upon daily oral exposure, which is not routinely investigated in chronic animal studies. A health risk from nanosized TiO2 particle consumption could not be excluded then.