Prestatiekenmerken van de bepaling van formaldehyde en 8-hydroxychinolinesulfaat
Cleven RFMJ Graaf M de
Cleven RFMJ
Graaf M de
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Series / Report no.
Open Access
Type
Report
Language
nl
Date of publication
1996-12-31
Year of publication
Research Projects
Organizational Units
Journal Issue
Title
Prestatiekenmerken van de bepaling van formaldehyde
en 8-hydroxychinolinesulfaat
Translated Title
Performance characteristics of the determination
of formaldehyde and 8-hydroxychinolinesulphate
Published in
Abstract
Een aantal prestatiekenmerken voor de bepaling van een
tweetal componenten waarvan de gehaltes regelmatig worden bepaald in
voornamelijk sera en vaccins, is nader vastgelegd. Het betreft juistheid,
precisie en nauwkeurigheid, de lineariteit van de kalibratiecurven,
aantoonbaarheidsgrens, en matrix-effecten op precisie en nauwkeurigheid van
de fotometrische bepalingen van formaldehyde en 8-hydroxy-chinolinesulfaat.
De nauwkeurigheid blijkt voor formaldehyde beter dan 5%, en voor
8-hydroxychinolinesulfaat beter dan 3% over vrijwel de gehele meetbereiken
van de methodes. De aantoonbaarheidsgrenzen bedragen 5 en 0,5 mumol/l voor
respectievelijk formaldehyde en
8-hydroxychinolinesulfaat.
Performance characteristics of the determinations of two components that are frequently analysed in sera and vaccines, have been established. It concerns trueness, precision and accuracy, the linearity of the calibration curves, the limit of detection and matrix effects on precision and accuracy of the photometric determinations of formaldehyde and 8-hydroxychinoline-sulphate. It appears that for formaldehyde the accuracy is better than 5%, and for 8-hydroxychinoline-sulphate the accuracy is better than 3% over nearly the whole concentration ranges covered by the methods. The limits of detection of the methods are 5 and 0.5 mumol/l for formaldehyde and 8-hydroxychinolinesulphate respectively, for the undiluted samples.
Performance characteristics of the determinations of two components that are frequently analysed in sera and vaccines, have been established. It concerns trueness, precision and accuracy, the linearity of the calibration curves, the limit of detection and matrix effects on precision and accuracy of the photometric determinations of formaldehyde and 8-hydroxychinoline-sulphate. It appears that for formaldehyde the accuracy is better than 5%, and for 8-hydroxychinoline-sulphate the accuracy is better than 3% over nearly the whole concentration ranges covered by the methods. The limits of detection of the methods are 5 and 0.5 mumol/l for formaldehyde and 8-hydroxychinolinesulphate respectively, for the undiluted samples.
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