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Differences by sex in IgG levels following infant and childhood vaccinations: An individual participant data meta-analysis of vaccination studies.
Boef, Anna G C ; van der Klis, Fiona R M ; Berbers, Guy A M ; Buisman, Anne-Marie ; Sanders, Elisabeth A M ; Kemmeren, Jeanet M ; van der Ende, Arie ; de Melker, Hester E ; Rots, Nynke Y ; Knol, Mirjam J
Boef, Anna G C
van der Klis, Fiona R M
Berbers, Guy A M
Buisman, Anne-Marie
Sanders, Elisabeth A M
Kemmeren, Jeanet M
van der Ende, Arie
de Melker, Hester E
Rots, Nynke Y
Knol, Mirjam J
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Series / Report no.
Open Access
Type
Article
Language
en
Date of publication
2018-01-08
Year of publication
Research Projects
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Journal Issue
Title
Differences by sex in IgG levels following infant and childhood vaccinations: An individual participant data meta-analysis of vaccination studies.
Translated Title
Published in
Vaccine 2018; 36(3):400-7
Abstract
If immune responses to vaccination differ between males and females, sex-specific vaccination schedules may be indicated. We systematically reanalysed childhood vaccination studies conducted in The Netherlands for sex-differences in IgG-responses. To assess the impact of potential sex-differences in IgG-responses, we explored sex-differences in vaccine failure/effectiveness and reactogenicity.
