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Cross-border spread of - and -positive : a European collaborative analysis of whole genome sequencing and epidemiological data, 2014 to 2019.

Ludden, Catherine
Lötsch, Felix
Alm, Erik
Kumar, Narender
Johansson, Karin
Albiger, Barbara
Huang, Te-Din
Denis, Olivier
Hammerum, Anette M
Hasman, Henrik
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Article
Language
en
Date of publication
2020-05-01
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Title
Cross-border spread of - and -positive : a European collaborative analysis of whole genome sequencing and epidemiological data, 2014 to 2019.
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Euro Surveill 2020; 25(20):pii.2000627
Abstract
Analysis of sequencing data for 143 blaNDM-1- and blaOXA-48-positive Klebsiella pneumoniae isolates from 13 European national collections and the public domain resulted in the identification of 15 previously undetected multi-country transmission clusters. For 10 clusters, cases had prior travel/hospitalisation history in countries outside of the European Union including Egypt, Iran, Morocco, Russia, Serbia, Tunisia and Turkey. These findings highlight the benefit of European whole genome sequencing-based surveillance and data sharing for control of antimicrobial resistance.
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