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Decay Rates of Maternal Tetanus, Diphtheria, and Pertussis Antibody Levels in Early and Moderate-to-Late Preterm and Term Infants at Birth and at Two Months.

Immink, Maarten M
van der Maas, Nicoline A T
Bekker, Mireille N
de Melker, Hester E
den Hartog, Gerco
Rots, Nynke Y
van Gageldonk, Pieter G M
Groenendaal, Floris
Sanders, Elisabeth A M
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Open Access
Type
Journal Article
Article
Language
en
Date of publication
2024-12-10
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Title
Decay Rates of Maternal Tetanus, Diphtheria, and Pertussis Antibody Levels in Early and Moderate-to-Late Preterm and Term Infants at Birth and at Two Months.
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Open Forum Infect Dis 2024; 12(1):ofae717
Abstract
A post hoc analysis of maternally derived antibodies at birth and age 2 months following second trimester maternal Tdap vaccination between 20 and 24 weeks' gestational age (GA) showed a faster decay rate of Tdap-related immunoglobulin G in early preterms born before 32 weeks' GA compared with moderate-to-late preterms and full-terms. This is different from previous studies and merits further research.
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