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Staat van Infectieziekten in Nederland, 2010(Rijksinstituut voor Volksgezondheid en Milieu RIVMJulius CentrumUniversitair Medisch Centrum UtrechtMinistry of Health of CuracaoGGD Curacao, 2011-10-24)In 2010 and the first half of 2011 the outbreak of mumps among students was the most striking event concerning infectious diseases in the Netherlands. This is concluded in the State of Infectious Diseases in 2010. The purpose of this report is to provide insight into developments of infectious diseases in the Dutch population. This report also describes international developments abroad that are relevant to the Netherlands. The information contained in this yearly publication is compiled by the RIVM for policymakers at the Ministry of Health, Welfare and Sport (VWS). One particular topic is highlighted each year in the State of Infectious Diseases. This time the focus is on the number of healthy life years lost (disease burden) due to infectious diseases. Information on disease burden helps policymakers to set priorities in the area of infectious disease control. It is difficult to compare disease burdens of different infectious diseases with each other. Some infectious diseases occur very frequently but are in general very mild, while other infectious diseases occur rarely but cause a high mortality. A health measure that combines these aspects of diseases is the Disability Adjusted Life Year (DALY). In this report we explain how the DALY can be calculated, which decisions and assumptions need to be made for this calculation and which aspects are important for infectious diseases in particular. To be able to generate reliable estimates of the disease burden of infectious diseases, future research is needed on the quality of data with regard to the frequency of occurrence of infectious diseases and the degree of underreporting. Preliminary estimates do already give a picture of the variation in disease burden between different infectious diseases.