• Sexually transmitted infections, including HIV, in the Netherlands in 2009

      Vriend HJ; Koedijk FDH; van den Broek IVF; van Veen MG; Op de Coul ELM; van Sighem AI; Verheij RA; van der Sande MAB; EPI ; LIS; cib (Rijksinstituut voor Volksgezondheid en Milieu RIVMsoa-centraSHMHiv-centraNederlands Instituut voor onderzoek van de gezondheidszorg NIVEL, 2010-06-18)
      Chlamydia. Chlamydia remains the sexually transmitted infection (STI) diagnosed most often among STI clinic attendees, with almost 10,000 new infections reported in 2009. Whilst there was an increase in the numbers of infections that occurred, the positivity rate remained stabile. Of the total heterosexual STI clinic attendees, 11 per cent had a chlamydia infection compared with 14 per cent in the group of heterosexuals younger than 25 years. Gonorrhoea. The number of gonorrhoea infections and the positivity rate has increased substantially compared with 2008. The main cause is the increase (28 percent) in gonorrhoea diagnoses in men having sex with men (MSM). In particular, the percentage of positive oral gonorrhoea tests among MSM increased. Notable here is the increase in gonorrhoea strains which are less sensitive to antibiotics. Syphilis. In 2009, the number of new diagnoses of syphilis decreased by 15 per cent compared with 2008. The percentage of positive tests also decreased. This decline is also visible in the long term trend. Syphilis in MSM accounted for 89 per cent of all syphilis diagnoses. HIV. There was again a slight decline in the number and proportion of positive HIV tests at the STI clinics. Since January 1st 2010, all STI clinic attendees have been tested for HIV, except those who explicitly refused, known as opting out testing. In 2009, 92 per cent of all STI clinic attendees who did not know their HIV status were tested for HIV. Among those MSM known to be HIV positive, 34 per cent were diagnosed with one or more STI in 2009. STI clinic attendees. In 2009, a total of 93,331 persons were tested at one of the STI clinics in the Netherlands. This was 6 per cent more than in 2008. There were especially more MSM who visited an STI clinic in 2009, an increase of 19 per cent compared with 2008. One or more STI was found in 13 per cent of the attendees (in 20 per cent of MSM and in 12 per cent of heterosexual attendees). These figures are comparable with previous years.
    • Staat van Infectieziekten in Nederland 2011

      Bijkerk P; van der Plas SM; van Asten L; Fanoy EB; Kroneman A; Kretzschmar MEE; EPI ; LIS; cib (Rijksinstituut voor Volksgezondheid en Milieu RIVM, 2012-11-08)
      In 2011 and the first half of 2012 outbreaks of mumps and pertussis were the most striking events concerning infectious diseases in the Netherlands. This is concluded in the State of Infectious Diseases in 2011. The purpose of this report is to provide insight into developments of infectious diseases in the Dutch population. This report also describes current international developments that are relevant to the Netherlands. The information contained in this yearly publication is compiled for policymakers at the Ministry of Health, Welfare and Sport (VWS). One particular topic is highlighted each year. This time the focus is on bioinformatics and its relevance for infectious disease research and public health. In bioinformatics biology, mathematics and computer science come together with the aim to unravel information coded in biological molecules. Development of advanced sequencing techniques in the laboratory and the availability of increasingly powerful computers make bioinformatics into a rapidly evolving research field. Data on the structure of DNA, RNA and proteins in pathogens are increasingly available in large quantities. Analysis software makes it possible to sort these complex data, to visualize and to interpret them, thus increasing our understanding of (molecular) epidemiology, the possibilities of pathogens to mutate, their interactions with their hosts and evolutionary strategies. This knowledge provides new perspectives for the control of infectious diseases. Bioinformatics is a diverse research field. Therefore it is important to set priorities in the development of bioinformatics expertise, diagnostic and research tools that contribute to infectious diseases control.