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    Pilot onderzoek naar effecten van verschillende doseringen histamine toegediend via vismonsters aan gezonde vrijwilligers

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    Authors
    Gelderen CEM van
    Tepas BCA
    Kistemaker C
    Ginkel LA van
    Savelkoul TJF
    Type
    Report
    Language
    nl
    
    Metadata
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    Title
    Pilot onderzoek naar effecten van verschillende doseringen histamine toegediend via vismonsters aan gezonde vrijwilligers
    Translated Title
    Pilot experiment to investigate the effects of several doses histamine administrated in fish samples to healthy volunteers
    Publiekssamenvatting
    Abstract niet beschikbaar
    The effects of histamine administrated in fish samples to 8 healthy volunteers (4 females and 4 males) have been studied. The fish samples contained 0, 45 or 90 mg histamine which had been metabolized by photobacteria in fish out of histidine, or 90 mg histamine added to fresh fish. The volunteers had the samples for breakfast in random order, with intervals of one week. Attention was paid to clinical symptoms. The pH of the stomach contents, the histamine concentration in plasma and the histamine metabolites in urine were also recorded.
    Sponsors
    VVP
    URI
    http://hdl.handle.net/10029/256123
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