Pilot onderzoek naar effecten van verschillende doseringen histamine toegediend via vismonsters aan gezonde vrijwilligers
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Type
OnderzoeksrapportLanguage
nl
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Pilot onderzoek naar effecten van verschillende doseringen histamine toegediend via vismonsters aan gezonde vrijwilligersTranslated Title
Pilot experiment to investigate the effects of several doses histamine administrated in fish samples to healthy volunteersPubliekssamenvatting
Abstract niet beschikbaarThe effects of histamine administrated in fish samples to 8 healthy volunteers (4 females and 4 males) have been studied. The fish samples contained 0, 45 or 90 mg histamine which had been metabolized by photobacteria in fish out of histidine, or 90 mg histamine added to fresh fish. The volunteers had the samples for breakfast in random order, with intervals of one week. Attention was paid to clinical symptoms. The pH of the stomach contents, the histamine concentration in plasma and the histamine metabolites in urine were also recorded.
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