Resultaten van een analyse van de Zutphen-studie in het kader van concurrerende doodsoorzaken
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Resultaten van een analyse van de Zutphen-studie in het kader van concurrerende doodsoorzakenTranslated Title
Results of an analysis of the Zutphen-studie concerning competing death risks.]Publiekssamenvatting
Competing death risks have been analysed with data from the Zutphen-cohort. The dependencies between the specific hazards are modelled using joint risk factors. The Zutphen-cohort consists of 878 men that have been followed since 1960. A survival analysis has been performed using the Cox proportional hazards and the logistic model. The authors show how time and time-effects can be fitted into these models. Separated models have been fitted for the total mortality and the specific death risks, for conditioning on age or on period, and for correction for entry time or not. Finally, the separated models for the specific death risks have been combined into one model of the total hazard. Two combination methods (a non-parametric and a parametric one) have been investigated. The combined model of the hazard rate has been used to show the differences between independent (substitutive) and dependent (competitive) death risks. Finally, the authors draw some conclusions on the analysis of dependent competing death risks.<br>Sponsors
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