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dc.contributor.authorHeisterkamp SH
dc.contributor.authorHoogenveen RT
dc.contributor.authorvan Strijp-Lockefeer NGWM
dc.contributor.authorHoekstra JA
dc.contributor.authorHavelaar AH
dc.contributor.authorMooijman KA
dc.date.accessioned2017-02-20T08:06:38
dc.date.issued1991-08-31
dc.identifier148602003
dc.description.abstractMicrobiological reference materials are being developed by the RIVM since several years. These materials consist of capsules filled with milkpowder artificially contaminated with a bacteria test strain of choice (i.e. Escherichia coli, Enterobacter cloacae, Salmonella typhimurium). Both from longterm stability tests, and from short-term challenge tests at different storage temperatures, it is clear that these materials cannot survive forever. Standard statistical techniques for quality control, assuming both a stable process and the Normal distribution cannot be used. In this report we will deal with these non-standard problems.<br>
dc.description.sponsorshipEG/BCR
dc.description.sponsorshipHIMH
dc.description.sponsorshipVHI
dc.format.extent48 p
dc.language.isoen
dc.publisherRijksinstituut voor Volksgezondheid en Milieu RIVM
dc.relation.ispartofRIVM Rapport 148602003
dc.relation.urlhttp://www.rivm.nl/bibliotheek/rapporten/148602003.html
dc.subject11nl
dc.subject91-4nl
dc.subjectcusum-methodnl
dc.subjectquasi-likelihood estimationnl
dc.subjectcfunl
dc.titleStability and homogeneity of microbiological reference materials: some statistical modelsen
dc.title.alternativeStabiliteit en homogeniteit van microbiologisch referentiemateriaal: enkele statistische modellennl
dc.typeReport
dc.date.updated2017-02-20T07:06:39Z
html.description.abstractMicrobiological reference materials are being developed by the RIVM since several years. These materials consist of capsules filled with milkpowder artificially contaminated with a bacteria test strain of choice (i.e. Escherichia coli, Enterobacter cloacae, Salmonella typhimurium). Both from longterm stability tests, and from short-term challenge tests at different storage temperatures, it is clear that these materials cannot survive forever. Standard statistical techniques for quality control, assuming both a stable process and the Normal distribution cannot be used. In this report we will deal with these non-standard problems.&lt;br&gt;


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