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    Theoretische en practische aspecten van het gebruik van micro-HPLC

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    Authors
    de Fluiter P
    Jansen EHJM
    Type
    Onderzoeksrapport
    Language
    nl
    
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    Title
    Theoretische en practische aspecten van het gebruik van micro-HPLC
    Translated Title
    Theoretical and practical aspects of micro-HPLC
    Publiekssamenvatting
    A practical and theoretical approach for the implementation of micro high performance liquid chromatography (HPLC) is described. A new simple and rapid test procedure was developed in wich a HPLC system can be validated for its suitability for micro-bore columns. It appeared that the detector flowcell is the most critical parameter, specially when compounds are separated with a small capacity factor. The main advantage of a miniaturized system in comparance with a conventional system is the higher mass-sensitivity and the low consumption of eluentia.<br>
    Publisher
    Rijksinstituut voor Volksgezondheid en Milieu RIVM
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    RIVM
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