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    Maximum Permissible Concentrations for polychlorinated biphenyls

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    Authors
    van Wezel AP
    Traas T
    Polder M
    Posthumus R
    van Vlaardingen P
    Crommentuijn T
    van de Plassche EJ
    Type
    Report
    Language
    en
    
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    Title
    Maximum Permissible Concentrations for polychlorinated biphenyls
    Translated Title
    Maximaal Toelaatbare Concentraties voor polychloorbifenylen
    Publiekssamenvatting
    In dit rapport worden voor verschillende polychloorbifenylen een maximaal toelaatbaar risiconiveau (MTR) en verwaarloosbaar risiconiveau (VR) afgeleid. Hiervoor zijn probalistische voedselweb modellen gebruikt. Toxiciteitsdata voor water organismen, zoogdieren en vogels zijn omgerekend in de bijbehorende toxische concentraties in het organisch koolstof van sediment of bodem. Omdat de verschillende typen studies op deze wijze worden uitgedrukt op dezelfde concentratie-as, kunnen ze met elkaar worden vergeleken en geintegreerd in een MTR. Omdat PCBs altijd in een mengsel voorkomen, en de vlakke PCBs worden verondersteld volgens eenzelfde toxicologisch werkingsmechanisme te werken en daarom concentratie-additief te zijn, is een mengsel-MTR afgeleid.<br>
    In this report maximal permissible concentrations (MPCs) and negligible concentrations (NCs) are derived for polychlorinated biphenyls (PCBs). In this derivation probabilistic food-web modeling was used. Toxicity data for aquatic organisms, mammals and birds were recalculated into equivalent toxic concentrations in the organic carbon of sediments or soils. In this way, all types of studies could be readily compared on the same concentration axis and could be integrated into one MPC. As PCBs always occur in a mixture and the planar PCBs are supposed to act via the same toxicological mechanism and thus to be concentration-additive, a mixture-MPC was derived.<br>
    Publisher
    Rijksinstituut voor Volksgezondheid en Milieu RIVM
    Sponsors
    DGM/SVS
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