The synthesis of [2-13C]2-nitropropane at room temperature and at atmospheric pressure
dc.contributor.author | Jacquemijns M | |
dc.contributor.author | Zomer G | |
dc.date.accessioned | 2012-12-12T14:55:37Z | |
dc.date.available | 2012-12-12T14:55:37Z | |
dc.date.issued | 1990-03-31 | |
dc.identifier | 328605004 | |
dc.identifier.uri | http://hdl.handle.net/10029/256978 | |
dc.description.abstract | In this report the synthesis of [2-13C]2-nitropropane at room temperature is described. [2-13C]Acetone was converted into the oxime with hydroxy hydrochloridelamine and sodium carbonate. Treatment with hypobromic acid resulted in 2-13C]2-bromo-2-nitropropane. Hydrogenation with sodium borohydride gave [2-13C]2-nitropropane in 14,3% overall yield.<br> | |
dc.description.sponsorship | RIVM | |
dc.format.extent | 15 p | |
dc.language.iso | en | |
dc.publisher | Rijksinstituut voor Volksgezondheid en Milieu RIVM | |
dc.relation.ispartof | RIVM Rapport 328605004 | |
dc.relation.url | http://www.rivm.nl/bibliotheek/rapporten/328605004.html | |
dc.subject | 20 | nl |
dc.title | The synthesis of [2-13C]2-nitropropane at room temperature and at atmospheric pressure | en |
dc.title.alternative | De synthese van [2-13C]2-nitropropaan bij kamertemperatuur en atmosferische druk | nl |
dc.type | Report | |
dc.date.updated | 2012-12-12T14:55:38Z | |
html.description.abstract | In this report the synthesis of [2-13C]2-nitropropane at room temperature is described. [2-13C]Acetone was converted into the oxime with hydroxy hydrochloridelamine and sodium carbonate. Treatment with hypobromic acid resulted in 2-13C]2-bromo-2-nitropropane. Hydrogenation with sodium borohydride gave [2-13C]2-nitropropane in 14,3% overall yield.<br> |