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    Application of the in vitro test on sister chromatid exchanges (SCE's) in the frame-work of the WHO-IPCS collaborative study on short-term tests for genotoxicity and carcinogenicity

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    Authors
    Went
    G.F.van
    Type
    Report
    Language
    en
    
    Metadata
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    Title
    Application of the in vitro test on sister chromatid exchanges (SCE's) in the frame-work of the WHO-IPCS collaborative study on short-term tests for genotoxicity and carcinogenicity
    Translated Title
    Toepassing van de in vitro test op "sister chromatid exchanges" (SCE's) in het kader van het WHO-IPCS ringonderzoek betreffende kortdurende testen voor genotoxiciteit en carcinogeniteit
    Publiekssamenvatting
    Hexamethylphosphoramide (HMPA), O-toluidine, Benzeen, Safrol en Caprolactam zijn getest in de in vitro SCE-test met V79 cellen. Caprolactam en benzeen waren negatief met en zonder metabolisering; de 3 andere stoffen waren positief. De resultaten van de duplo- experimenten kwamen zeer goed overeen. De afwezigheid van mycoplasma in de V79 cellen werd geverifieerd.
    Abstract not available
    Sponsors
    RIVM
    WHO
    URI
    http://hdl.handle.net/10029/257202
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