Application of the in vitro test on sister chromatid exchanges (SCE's) in the frame-work of the WHO-IPCS collaborative study on short-term tests for genotoxicity and carcinogenicity
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Type
OnderzoeksrapportLanguage
en
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Show full item recordTitle
Application of the in vitro test on sister chromatid exchanges (SCE's) in the frame-work of the WHO-IPCS collaborative study on short-term tests for genotoxicity and carcinogenicityTranslated Title
Toepassing van de in vitro test op "sister chromatid exchanges" (SCE's) in het kader van het WHO-IPCS ringonderzoek betreffende kortdurende testen voor genotoxiciteit en carcinogeniteitPubliekssamenvatting
Hexamethylphosphoramide (HMPA), O-toluidine, Benzeen, Safrol en Caprolactam zijn getest in de in vitro SCE-test met V79 cellen. Caprolactam en benzeen waren negatief met en zonder metabolisering; de 3 andere stoffen waren positief. De resultaten van de duplo- experimenten kwamen zeer goed overeen. De afwezigheid van mycoplasma in de V79 cellen werd geverifieerd.Abstract not available
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RIVMWHO
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