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dc.contributor.authorvan de Laar MJW
dc.contributor.authorvan Duynhoven YTHP
dc.contributor.authorvan Klingeren B
dc.contributor.authorDessens-Kroon M
dc.contributor.authorVerheuvel M
dc.date.accessioned2014-01-17T13:39:01
dc.date.issued1993-08-31
dc.identifier441500002
dc.description.abstractThis report describes a study which was carried out to investigate an epidemic of gonococci with resistance to penicillin and tetracyclin (TRNG/PPNG). This study involved all PPNG-isolates which were sent in by five laboratories from Amsterdam, Rotterdam and The Hague in 1989-1990. The epidemic of TRNG/PPNG was found to be related mainly to three strains: NR/IB-6, PRO/IA-3, PRO/IA-6 with the plasmid pattern 3.2+25.2. The introduction of TRNG/PPNG presumably took place in The Hague in 1988. Independent risk factors of an infection due to TRNG/PPNG were for men: age above 40 years, and sexual contact with a prostitute (only for men in Rotterdam and The Hague). No relation with prostitution was found for men in Amsterdam. Independent risk factors were for women: age above 40 years and Turkish or Latin American nationality. Strains from The Hague were also independently correlated to TRNG/PPNG. Further spread of resistant strains seems to be related to prostitution, but only in Rotterdam and The Hague. The outbreak of TRNG/PPNG underlined the necessity for a continuous surveillance of resistance of gonococci including some background variables of patients.<br>
dc.description.sponsorshipGHI
dc.description.sponsorshipRIVM
dc.format.extent46 p
dc.language.isonl
dc.publisherRijksinstituut voor Volksgezondheid en Milieu RIVM
dc.relation.ispartofRIVM Rapport 441500002
dc.relation.urlhttp://www.rivm.nl/bibliotheek/rapporten/441500002.html
dc.subject04nl
dc.subjectneisseria gonorrhoeaenl
dc.subjectgonokokkennl
dc.subjectresistentienl
dc.subjectantibioticanl
dc.subjectpenicillinenl
dc.subjecttetracyclinenl
dc.subjectepidemiologienl
dc.subjectneisseria gonorrhoeaeen
dc.subjectgonorrheaen
dc.subjectmicrobial drug resistanceen
dc.subjectantibioticsen
dc.subjectpenicillinesen
dc.subjecttetracyclineen
dc.subjectepidemiologyen
dc.titleEen epidemische verheffing van gonokokken met resistentie tegen penicilline en tetracylinenl
dc.title.alternative[An epidemic of gonococci with resistance to both penicillin and tetracyclin.]en
dc.typeReport
dc.date.updated2014-01-17T12:41:18Z
html.description.abstractThis report describes a study which was carried out to investigate an epidemic of gonococci with resistance to penicillin and tetracyclin (TRNG/PPNG). This study involved all PPNG-isolates which were sent in by five laboratories from Amsterdam, Rotterdam and The Hague in 1989-1990. The epidemic of TRNG/PPNG was found to be related mainly to three strains: NR/IB-6, PRO/IA-3, PRO/IA-6 with the plasmid pattern 3.2+25.2. The introduction of TRNG/PPNG presumably took place in The Hague in 1988. Independent risk factors of an infection due to TRNG/PPNG were for men: age above 40 years, and sexual contact with a prostitute (only for men in Rotterdam and The Hague). No relation with prostitution was found for men in Amsterdam. Independent risk factors were for women: age above 40 years and Turkish or Latin American nationality. Strains from The Hague were also independently correlated to TRNG/PPNG. Further spread of resistant strains seems to be related to prostitution, but only in Rotterdam and The Hague. The outbreak of TRNG/PPNG underlined the necessity for a continuous surveillance of resistance of gonococci including some background variables of patients.&lt;br&gt;


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