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dc.contributor.authorHeisterkamp SH
dc.contributor.authorOlling M
dc.date.accessioned2012-12-12T16:56:27Z
dc.date.available2012-12-12T16:56:27Z
dc.date.issued1996-12-31
dc.identifier604502001
dc.identifier.urihttp://hdl.handle.net/10029/258373
dc.description.abstractA study is undertaken of the feasibility of a general model or standard procedure to assess the exposure to xenobiotics, and possibly the effects, in food. An inventarisation is made of the research in the Netherlands with regard to this route of exposure. Quality and adequacy of the existing models and databases are judged and the issues as internal exposure and the effect of food preparation are considered. The conclusion is that the existing models, operational at RIKILT-DLO and LEO-RIVM should be adapted in such a way that exposure can be quantified in different ways together with their uncertainties. The importance of the maintenance of existing databases is stressed. A report on the construction of a general model and its validation is planned to be published in 1997.
dc.description.sponsorshipIGB
dc.format.extent25 p
dc.language.isonl
dc.relation.ispartofRIVM Rapport 604502001
dc.relation.urlhttp://www.rivm.nl/bibliotheek/rapporten/604502001.html
dc.subject03nl
dc.subjecthazardous substancesen
dc.subjectfooden
dc.subjectexposureen
dc.subjectmodellingen
dc.subjectevaluation studiesen
dc.titleHaalbaarheidsstudie Humane Blootstelling Voedingnl
dc.title.alternativeFeasibility Study Human Exposure to Nutritionen
dc.typeOnderzoeksrapport
dc.contributor.departmentLBO
dc.date.updated2012-12-12T16:56:27Z
html.description.abstractDe haalbaarheid van een generiek model c.q. standaardprocedure ter beoordeling van de blootstelling aan xenobiotica in voeding, en waar mogelijk de effecten daarvan, is onderzocht. Een inventarisatie van Nederlands onderzoek op dit gebied is gemaakt. Kwaliteit en toepasbaarheid van bestaande modellen en gegevensbestanden worden beoordeeld en er is aandacht besteed aan punten zoals interne blootstelling en de effecten van bereiding. De conclusie is dat bestaande modellen zoals deze bestaan bij het RIKILT-DLO en LEO-RIVM zodanig aangepast moeten worden dat verschillende blootstellingsmaten kunnen worden uitgerekend met hun onzekerheid. In de loop van 1997 zal een rapport over een generiek model verschijnen.
html.description.abstractA study is undertaken of the feasibility of a general model or standard procedure to assess the exposure to xenobiotics, and possibly the effects, in food. An inventarisation is made of the research in the Netherlands with regard to this route of exposure. Quality and adequacy of the existing models and databases are judged and the issues as internal exposure and the effect of food preparation are considered. The conclusion is that the existing models, operational at RIKILT-DLO and LEO-RIVM should be adapted in such a way that exposure can be quantified in different ways together with their uncertainties. The importance of the maintenance of existing databases is stressed. A report on the construction of a general model and its validation is planned to be published in 1997.


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