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    Investigation of a pertussis outbreak in the province of Bam, Burkino Faso, January 1991

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    Authors
    Rumke HC
    Oostvogel PM
    Schlumberger M
    Type
    Report
    Language
    en
    
    Metadata
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    Title
    Investigation of a pertussis outbreak in the province of Bam, Burkino Faso, January 1991
    Translated Title
    Onderzoek naar een kinkhoest-epidemie in de provincie Bam, Burkino Faso, januari 1991
    Publiekssamenvatting
    Abstract niet beschikbaar
    A localized outbreak of pertussis in a part of the Bam province, Burkino Faso (West Africa) has been investigated in order to confirm the clinical diagnosis with laboratory methods, and to study the protective efficacy of the vaccine. In the affected area childhood immunization are given according to a simplified vaccination schedule with only two doses of a quadruple DTCP (DPT-IPV) vaccine (against diphteria, tetanus, pertussis and poliomyelitis). A total of 115 children was studied (interview, serology, classical culture, PCR test). The clinical diagnosis could be confirmed in a number of children by serology. Among children of 5 years and older some had received two DTCP caccinations. Younger children seemed to be protected better against pertussis. The numbers of children studied are too small however for a precise estimate of pertussis vaccin efficacy in this particular immunization program with simplified schedule.
    Sponsors
    RIVM
    URI
    http://hdl.handle.net/10029/258638
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