Mutagene stoffen en risico's voor natuurlijke populaties. Onderzoek met Daphnia magna als modelorganisme. II. Experimenten met een mutagene stof
dc.contributor.author | Vaal MA | |
dc.contributor.author | Breedijk I | |
dc.contributor.author | Dekker MP | |
dc.contributor.author | Mout HCA | |
dc.contributor.author | Kramers PGN | |
dc.contributor.author | Roghair CJ | |
dc.date.accessioned | 2017-02-20T07:13:48 | |
dc.date.issued | 1992-12-31 | |
dc.identifier | 719102021 | |
dc.description.abstract | Daphnia magna is used as a model organism to study the consequences of the impact of mutagenic chemicals to natural populations. Adult daphnids were exposed to a mutagenic test compound to test whether their offspring showed effects of induced mutations at exposure levels lower than the No Observed Effect Concentration for growth and reproduction. Life-history parameters were used as test parameters. A concentration-related toxic effect to reproduction could be measured reproducibly in the exposed adult daphnids. However, no indication of a mutagenic effect could be detected in their offspring. This may have been due to the inadequateness of the system to detect induced genetic change.<br> | |
dc.description.sponsorship | DGM/SVS | |
dc.description.sponsorship | STIMTOX | |
dc.format.extent | 38 p | |
dc.language.iso | nl | |
dc.publisher | Rijksinstituut voor Volksgezondheid en Milieu RIVM | |
dc.relation.ispartof | RIVM Rapport 719102021 | |
dc.relation.url | http://www.rivm.nl/bibliotheek/rapporten/719102021.html | |
dc.subject | 07 | nl |
dc.subject | mutageniteit | nl |
dc.subject | toxische stoffen | nl |
dc.subject | ecotoxicologie | nl |
dc.subject | voortplanting | nl |
dc.subject | dosis-effectrelatie | nl |
dc.subject | nel | nl |
dc.subject | toetsorganisme | nl |
dc.subject | watervlooien | nl |
dc.subject | mutagenicity | en |
dc.subject | toxic substances | en |
dc.subject | ecotoxicology | en |
dc.subject | reproduction | en |
dc.subject | dose effect relation | en |
dc.subject | nel | en |
dc.subject | monitoring organisms | en |
dc.subject | daphnia | en |
dc.subject | life-history parameters | en |
dc.title | Mutagene stoffen en risico's voor natuurlijke populaties. Onderzoek met Daphnia magna als modelorganisme. II. Experimenten met een mutagene stof | nl |
dc.title.alternative | [Mutagenic substances and natural populations at risk. Research with Daphnia magna as a model organism. II. Experiments with a mutagenic substance.] | en |
dc.type | Report | |
dc.date.updated | 2017-02-20T06:13:48Z | |
html.description.abstract | Daphnia magna is used as a model organism to study the consequences of the impact of mutagenic chemicals to natural populations. Adult daphnids were exposed to a mutagenic test compound to test whether their offspring showed effects of induced mutations at exposure levels lower than the No Observed Effect Concentration for growth and reproduction. Life-history parameters were used as test parameters. A concentration-related toxic effect to reproduction could be measured reproducibly in the exposed adult daphnids. However, no indication of a mutagenic effect could be detected in their offspring. This may have been due to the inadequateness of the system to detect induced genetic change.<br> |