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dc.contributor.authorJong APJM de
dc.contributor.authorLiem AKD
dc.date.accessioned2012-12-12T19:49:59Z
dc.date.available2012-12-12T19:49:59Z
dc.date.issued1991-08-31
dc.identifier730501035
dc.identifier.urihttp://hdl.handle.net/10029/260235
dc.description.abstractAbstract niet beschikbaar
dc.description.abstractThis report describes the results of a WHO-coordinated interlaboratory comparison study on the analysis of dioxins and PCBs in mother's milk and human blood. The study is biannually organised by the WHO, Regional Office for Europe (Copenhagen) and is aiming at the identification of laboratories capable of the analysis of dioxins and related compounds at a good, internationally accepted standard. In the present study, nineteen laboratories from Europe and North- America have participated for dioxins in mother's milk, sixteen for dioxins in blood and ten and sic for the analysis of PCBs in mother's milk and human blood, respectively. The study consisted of the analysis of three different pools of milk and blood, two of which contained added PCDD/Fs. One of the pools was sent after the results of two previous pools have been reported (test for reproducability). Results were evaluated on the basis of statistical analysis in terms of repeatability, reproducibility and accuracy. In general, coefficients of varation (CV) were better for analysis in mother's milk than for the lower levels in blood. Limits for the qualification of methods were average coefficients of variation of < 20% for analysis of PCBs in milk and blood, <30% for dioxins in milk and <40% for dioxins in blood. All our four methods have been qualified. In the final ranking of laboratories, RIVM-LOC methods scored first positions for PCBs and dioxins in milk and for PCBs in blood and a third position for the analysis of dioxins in blood. The average CVs were 12.4, 3.3, 8.7 and 11,3% for analysis for PCBs and dioxins in milk and blood, respectively.
dc.description.sponsorshipHIMH
dc.description.sponsorshipHIGB
dc.format.extent19 p
dc.language.isoen
dc.relation.ispartofRIVM Rapport 730501035
dc.relation.urlhttp://www.rivm.nl/bibliotheek/rapporten/730501035.html
dc.subject11nl
dc.subject91-3nl
dc.subjectdioxinesnl
dc.subjectmoedermelknl
dc.subjectbloednl
dc.subjectdioxinsnl
dc.subjecthuman milk and bloodnl
dc.subject914nl
dc.titleWHO Coordination Interlaboratory Calibration Study on the Analysis of Dioxins and PCB&apos;s in Human Milk and Blooden
dc.title.alternativeWHO Gecoordineerd interlaboratorium onderzoek over de analyse van dioxines and PCB&apos;s in moedermelk en bloednl
dc.typeReport
dc.date.updated2012-12-12T19:50:00Z
html.description.abstractAbstract niet beschikbaar
html.description.abstractThis report describes the results of a WHO-coordinated interlaboratory comparison study on the analysis of dioxins and PCBs in mother&apos;s milk and human blood. The study is biannually organised by the WHO, Regional Office for Europe (Copenhagen) and is aiming at the identification of laboratories capable of the analysis of dioxins and related compounds at a good, internationally accepted standard. In the present study, nineteen laboratories from Europe and North- America have participated for dioxins in mother&apos;s milk, sixteen for dioxins in blood and ten and sic for the analysis of PCBs in mother&apos;s milk and human blood, respectively. The study consisted of the analysis of three different pools of milk and blood, two of which contained added PCDD/Fs. One of the pools was sent after the results of two previous pools have been reported (test for reproducability). Results were evaluated on the basis of statistical analysis in terms of repeatability, reproducibility and accuracy. In general, coefficients of varation (CV) were better for analysis in mother&apos;s milk than for the lower levels in blood. Limits for the qualification of methods were average coefficients of variation of &lt; 20% for analysis of PCBs in milk and blood, &lt;30% for dioxins in milk and &lt;40% for dioxins in blood. All our four methods have been qualified. In the final ranking of laboratories, RIVM-LOC methods scored first positions for PCBs and dioxins in milk and for PCBs in blood and a third position for the analysis of dioxins in blood. The average CVs were 12.4, 3.3, 8.7 and 11,3% for analysis for PCBs and dioxins in milk and blood, respectively.


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