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dc.contributor.authorVermeire TG
dc.contributor.authorKroese ED
dc.contributor.authorMeijer GW
dc.contributor.authorMohn GR
dc.contributor.authorNotenboom J
dc.contributor.authorPeijnenburg WJGM
dc.contributor.authorPiersma AH
dc.contributor.authorRoghair CJ
dc.date.accessioned2013-06-13T22:08:25
dc.date.issued1993-05-31
dc.identifier679102018
dc.description.abstractThis report is a continuation of the description of the initial hazard and risk assessment process for new substances at the National Institute of Public Health and Environmental Protection (RIVM) in the Netherlands. This assessment pertains to both man and the environment and is performed within the framework of the European Community (EC) Directive 79/831/EEC and the ensuing Dutch Chemical Substances Act. The first report (no. 679102006) was restricted to the assessment of substances on the basis of the tests required at a market or production volume up to 100 tonnes per year or 500 tonnes cumulative (level O or base set level). The present publication pertains to the post base set assessment, specifically on the basis of tests required at market volumes of 100 to 1000 tonnes per year or 500 to 5000 tonnes cumulative (level 1). Step by step the essential elements of the hazard and risk assessment process are discussed in so far these have not yet been dealt with in the earlier report. These elements include organizational aspects, data requirements, the determination of the acceptability of the data received, the scientific evaluation of the test methods and results, the exposure assessment, the comparison of exposure and toxicity data, and the requirements for further testing following the level 1 assessment.<br>
dc.description.sponsorshipDGM/SVS Zandt PTJ van der
dc.format.extent85 p
dc.language.isoen
dc.publisherRijksinstituut voor Volksgezondheid en Milieu RIVM
dc.relation.ispartofRIVM Rapport 679102018
dc.relation.urlhttp://www.rivm.nl/bibliotheek/rapporten/679102018.html
dc.subject12nl
dc.subjectchemicalieennl
dc.subjectrisiconl
dc.subjectgezondheidnl
dc.subjectmilieunl
dc.subjectrisico analysenl
dc.subjectnieuwe materialennl
dc.subjectveiligheidnl
dc.subjectchemicalsen
dc.subjecthealth risksen
dc.subjectrisksen
dc.subjectenvironmenten
dc.subjectrisk analysisen
dc.subjectnew materialsen
dc.subjectsafetyen
dc.titleInitial assessment of the hazards and risks of new chemicals to man and the environment. Part IIen
dc.title.alternative[Primaire beoordeling van de gevaren en risico&apos;s van nieuwe stoffen voor mens en milieu. Deel II.]nl
dc.typeReport
dc.date.updated2013-06-13T20:08:27Z
html.description.abstractThis report is a continuation of the description of the initial hazard and risk assessment process for new substances at the National Institute of Public Health and Environmental Protection (RIVM) in the Netherlands. This assessment pertains to both man and the environment and is performed within the framework of the European Community (EC) Directive 79/831/EEC and the ensuing Dutch Chemical Substances Act. The first report (no. 679102006) was restricted to the assessment of substances on the basis of the tests required at a market or production volume up to 100 tonnes per year or 500 tonnes cumulative (level O or base set level). The present publication pertains to the post base set assessment, specifically on the basis of tests required at market volumes of 100 to 1000 tonnes per year or 500 to 5000 tonnes cumulative (level 1). Step by step the essential elements of the hazard and risk assessment process are discussed in so far these have not yet been dealt with in the earlier report. These elements include organizational aspects, data requirements, the determination of the acceptability of the data received, the scientific evaluation of the test methods and results, the exposure assessment, the comparison of exposure and toxicity data, and the requirements for further testing following the level 1 assessment.&lt;br&gt;


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