Bepaling van de beta-adrenerge bindingskarakteristiek in humane- en rattelymphocyten
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Bepaling van de beta-adrenerge bindingskarakteristiek in humane- en rattelymphocytenTranslated Title
[Assay of beta-adrenergic bindingcharacteristics in human-and rat lymphocytes.]Publiekssamenvatting
Bindingcharacteristics of beta-adrenergic receptors were assayed in membranes of human-and rat lymphocytes using iodocyanopindolol (ICYP) as radioactive labelled ligand. The affinity constant (Kd) of ICYP for human and rat adrenergic receptors was respectively 8.5 and 16.5 pM. Total number of receptors (Bmax) in the species studied were respectively 70 and 160 fmole/mg protein.<br>Sponsors
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