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dc.contributor.authorvan Loveren H
dc.contributor.authorVos JG
dc.date.accessioned2012-12-12T23:56:07Z
dc.date.available2012-12-12T23:56:07Z
dc.date.issued1992-01-31
dc.identifier158801001
dc.identifier.urihttp://hdl.handle.net/10029/262346
dc.description.abstractIn this report examples of studies that have revealed immunotoxicity of chemicals are discussed. Based on these studies, the efficacy for identifying potential immunotoxicity of studies carried out according to this guideline is evaluated. Based on this evaluation it is recommended that additional immunologic parameters are included in this guideline, in order to increase the power of the test so that potential adverse effects of exposure to the compound in terms of an affected immune system are indicated during the testing procedure.<br>
dc.description.sponsorshipVVP
dc.format.extent32 p
dc.language.isoen
dc.publisherRijksinstituut voor Volksgezondheid en Milieu RIVM
dc.relation.ispartofRIVM Rapport 158801001
dc.relation.urlhttp://www.rivm.nl/bibliotheek/rapporten/158801001.html
dc.subject07nl
dc.subjecttoxiciteitstestennl
dc.subjectimmunotoxiciteitnl
dc.subjectrichtlijnnl
dc.subjectevaluatienl
dc.subjectoecdnl
dc.subjecttoxicity testingen
dc.subjectimmunotoxicityen
dc.subjectguidelinesen
dc.subjectevaluationen
dc.titleEvaluation of OECD guideline 407 for assessment of toxicity of chemicals with respect to potential adverse effects to the immune systemen
dc.title.alternativeEvaluatie van de OECD richtlijn 407 t.a.v. immunotoxiciteitnl
dc.typeReport
dc.date.updated2012-12-12T23:56:07Z
html.description.abstractIn this report examples of studies that have revealed immunotoxicity of chemicals are discussed. Based on these studies, the efficacy for identifying potential immunotoxicity of studies carried out according to this guideline is evaluated. Based on this evaluation it is recommended that additional immunologic parameters are included in this guideline, in order to increase the power of the test so that potential adverse effects of exposure to the compound in terms of an affected immune system are indicated during the testing procedure.&lt;br&gt;


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